Gut-Brain Reset by Microbiome Labs – Dual-Action Probiotic Support for the Gut-Brain Axis
Gut-Brain Reset by Microbiome Labs is a clinically supported probiotic supplement designed to address the powerful connection between digestive health and emotional well-being. Formerly known as Zenbiome Dual, this gut-brain axis formula combines two rigorously studied Bifidobacterium strains to deliver around-the-clock digestive comfort while simultaneously supporting mood self-regulation and healthy stress responses. For individuals experiencing the frustrating overlap of GI discomfort and psychological tension, Gut-Brain Reset offers a science-backed, two-in-one solution in a simple two-capsule daily serving.
Key Gut-Brain Reset Benefits
- Supports digestive comfort, including relief from occasional abdominal discomfort, gas, bloating, diarrhea, and/or constipation
- Targets the gut-brain axis to address the bidirectional relationship between GI function and mental well-being
- Supports mood self-regulation and helps the body manage occasional stress
- Helps maintain cortisol levels already within a normal range to support healthy energy, vitality, and mental acuity
- Supports balanced sleep and promotes healthy gut microbiome diversity and function
How Gut-Brain Reset Works
The gut and brain communicate constantly through a complex network of nerves, hormones, and immune signals known as the gut-brain axis. Functional GI disturbances — characterized by episodes of bloating, abdominal discomfort, and irregular bowel habits — are frequently accompanied by mood imbalances and heightened psychological stress. Gut-Brain Reset addresses this connection at its source by delivering two complementary, clinically studied Bifidobacterium strains that work together across different aspects of this pathway. Together, they support microbiome balance, tryptophan metabolism, cortisol regulation, and normal digestive processes, providing comprehensive dual-action support throughout the day and night.
Key Functional Ingredients Include:
- Bifidobacterium longum 1714™ (Zenbiome Cope™): A clinically studied psychobiotic strain shown in placebo-controlled and randomized double-blind trials to support cortisol regulation, reduce perceived stress, promote relaxation, enhance mood, and support healthy sleep quality — particularly during periods of stress.
- Bifidobacterium longum 35624® (Zenbiome Sleep™): A well-researched probiotic strain with demonstrated ability to support relief from occasional GI discomfort, including abdominal distension and irregular bowel habits, while also contributing to improved morning cortisol awakening response as a physiological marker of healthy stress adaptation.
Gut-Brain Reset is formulated without common allergens and is suitable for individuals with sensitivities. The vegetable capsule delivery system ensures this formula is accessible to a wide range of dietary preferences.
Gut-Brain Reset Is Formulated For
- Adults experiencing occasional GI discomfort — including gas, bloating, abdominal pain, or irregular bowel habits — alongside mood or stress imbalances
- Individuals seeking a psychobiotic approach to supporting both gut health and emotional resilience simultaneously
- Those looking to support healthy cortisol levels, energy, and mental clarity through gut microbiome interventions
- Anyone interested in clinically validated probiotic strains with published human research supporting their efficacy
- Individuals who prefer a clean, allergen-conscious supplement free from soy, dairy, and corn
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners. You may also want to explore our GI Health Supplements collection.
Recommendation: Take 2 capsules daily with a meal, or as directed by your healthcare practitioner.
Serving Size: 2 Capsules
Servings Per Container: 30
Proprietary Probiotic Blend ... 67.5 mg (10 Billion CFU*)
— Bifidobacterium longum 1714™
— Bifidobacterium longum 35624®
*At time of manufacturing
Other Ingredients: Vegetable Capsule (Hypromellose, Water), Cellulose, Magnesium Stearate.
Does not contain: Soy, milk, or corn.
Warnings/Cautions: If you are pregnant or nursing, taking any medication, or have a medical condition, consult your doctor before using this product. Keep out of reach of children. Do not use if safety seal is broken or missing.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Click here to view Product Info Sheet
References:
- DOI: 10.1038/tp.2016.191 — Bifidobacterium longum 1714® supported cortisol levels and reduced perceived stress in a placebo-controlled study (22 participants, 4 weeks).
- DOI: 10.14309/ajg.0000000000000203 — Randomized, double-blind, placebo-controlled trial (40 participants, 4 weeks) demonstrated B. longum 1714® supported relaxation, reduced stress, enhanced mood, and promoted healthy brainwave activity at rest.
- DOI: 10.1016/j.bbih.2020.100174 — Double-blind, randomized, placebo-controlled crossover study (20 participants, 4 weeks) found significant improvements in sleep quality and duration during exam stress in the probiotic group.
- DOI: 10.1111/nmo.14477 — Open-label study (40 participants, 8 weeks) combining B. longum 1714® and B. longum 35624® found 82% of subjects had significantly improved GI outcomes, with notable improvements in cortisol awakening response after 4 weeks.
Frequently Asked Questions About Gut-Brain Reset
What are the main health benefits of Zenbiome Dual?
Zenbiome Dual is a specialized probiotic designed to support both digestive health and emotional well-being through the gut-brain axis. It contains clinically studied strains of Bifidobacterium longum that help promote digestive comfort, regular bowel function, and a balanced gut microbiome. Many users choose Zenbiome Dual to help manage occasional bloating, gas, abdominal discomfort, and digestive irregularity while also supporting healthy mood regulation, stress resilience, and overall wellness. The formula provides dual-action support for both gastrointestinal and mental well-being.
How does Zenbiome Dual work in the body?
Zenbiome Dual works by targeting the gut-brain axis, the communication network between the digestive system and the nervous system. It delivers two clinically researched probiotic strains, Bifidobacterium longum 1714™ and Bifidobacterium longum 35624®, which help support microbial balance in the digestive tract. These beneficial bacteria help maintain healthy digestive processes while also influencing signals that support mood, stress response, mental clarity, and emotional balance. By promoting a healthier microbiome, Zenbiome Dual supports both gastrointestinal comfort and overall well-being.
Who should consider taking Zenbiome Dual?
Zenbiome Dual may be a good option for adults seeking support for both digestive and emotional wellness. Individuals who experience occasional bloating, gas, constipation, diarrhea, abdominal discomfort, or digestive upset related to stress may find this formula beneficial. It may also appeal to those looking for gut-brain axis support, healthy mood regulation, improved stress resilience, and balanced digestive function. Because the formula combines two clinically studied probiotic strains, it is often selected by people who want a more targeted approach than a general probiotic supplement.
Are there any side effects associated with Zenbiome Dual?
Zenbiome Dual is generally well tolerated when used as directed. As with many probiotic supplements, some individuals may experience mild digestive changes during the first few days of use, including temporary gas, bloating, or changes in bowel habits as the gut microbiome adapts. These effects are typically mild and short-lived. Individuals who are pregnant, nursing, taking medications, or managing a medical condition should consult their healthcare provider before starting any new supplement. If unexpected symptoms occur, discontinue use and seek professional guidance.
