Licorice Plus® by Metagenics – Cortisol Metabolism Support
Licorice Plus® combines four botanical roots in a tablet formulated for cortisol metabolism support. Rather than supplying cortisol or another hormone, this formula provides standardized licorice root extract alongside ashwagandha, rehmannia, and Chinese yam. It is intended for a practitioner-guided approach to managing everyday stress, with particular attention to whether a glycyrrhizic-acid-containing supplement is appropriate for you.
Key Licorice Plus Benefits
- Designed to support healthy cortisol metabolism as part of the body's response to stress.
- Provides standardized licorice root extract with a specified glycyrrhizic acid content, making its composition clear rather than relying on an unspecified root powder.
- Combines ashwagandha root extract with a concentrated rehmannia and Chinese yam blend in one convenient tablet.
How Licorice Plus Works
Cortisol metabolism involves converting cortisol into other compounds, including cortisone. Glycyrrhizin, a constituent of licorice, can inhibit an enzyme involved in that conversion in the kidney. This is a specific biochemical action, not a promise to normalize everyone's cortisol levels. The same action makes blood-pressure considerations important when selecting botanical stress support. Practitioner guidance helps distinguish an appropriate use from simply choosing a product because you feel stressed.
Key Functional Ingredients Include:
- Licorice root: Supplies glycyrrhizic acid as the formula's defining constituent. This is not a deglycyrrhizinated licorice formula, so it should not be treated as interchangeable with DGL products.
- Ashwagandha root: Adds a botanical used in stress-support formulas. Human research on ashwagandha has examined stress responses, but used a different extract and dose; those results do not establish the effects of this combination.
- Rehmannia and Chinese yam: Complete the four-botanical formula within a shared 4:1 extract blend. The combined blend amount is disclosed; individual amounts are not separately specified.
The 60-tablet supplement has a one-tablet serving. Extract ratios describe concentration, not a reason to increase your dose. Review the complete ingredient panel and warnings with your practitioner, especially when comparing it with other licorice-containing products.
Licorice Plus Is Formulated For
- People whose practitioner has recommended targeted support for cortisol metabolism.
- Those seeking a botanical option within a broader, individualized stress-management routine.
- People who prefer once-daily tablet support and can follow the product's medication precautions and health-related restrictions.
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners, led by Carolyn Mulally BS, RN, HN-BC. You may also wish to explore our Stress Products and Supplements collection.
Recommendation: Take one tablet daily or as directed by your healthcare practitioner.
Serving Size: 1 Tablet
Servings Per Container: 60
Licorice (Glycyrrhiza glabra) Root Extract [standardized to 25% (75 mg) glycyrrhizic acid] ... 300 mg**
Ashwagandha (Withania somnifera) Root 15:1 Extract (containing withanolides) ... 50 mg**
A 4:1† Herbal Extract Blend of: ... 250 mg**
Rehmannia (Rehmannia glutinosa) Root
Chinese Yam (Dioscorea oppositifolia) Root
**Daily Value not established.
†Equivalent to 1000 mg raw, dried, unprocessed herbs.
Other Ingredients: Microcrystalline cellulose, dicalcium phosphate, croscarmellose sodium, stearic acid (vegetable), coating (hydroxypropylmethylcellulose, hydroxypropylcellulose, and medium-chain triglycerides) and silicon dioxide.
Storage: Dry Place
Frequently Asked Questions About Licorice Plus
What are the main benefits of Licorice Plus?
Licorice Plus is designed to support healthy cortisol metabolism as part of a practitioner-guided stress-support plan. Its distinguishing ingredient is licorice extract standardized for glycyrrhizic acid, accompanied by ashwagandha and a rehmannia–Chinese yam blend. It is not a hormone replacement or a promise to bring cortisol to a particular level. The most useful benefit discussion starts with your goals and whether this specific type of botanical formula is suitable for you.
Who should consider Licorice Plus?
Consider this formula when your healthcare practitioner recommends its particular approach to cortisol metabolism, rather than selecting it for stress alone. The manufacturer says not to use it during pregnancy or nursing, or with heart disease or hypertension. If you take medication, consult your practitioner before use. Bring a list of your other supplements as well, especially other licorice products, so the full combination can be reviewed before you begin.
Are there side effects or precautions with Licorice Plus?
Yes. Glycyrrhizic acid affects cortisol metabolism, and the manufacturer warns that extended use at the stated levels may elevate blood pressure. Follow the one-tablet daily directions unless your practitioner directs otherwise; the warning threshold is not an alternative recommended dose. Do not use during pregnancy or nursing, or if you have heart disease or hypertension. Consult your practitioner before combining it with medication, and seek individualized advice if you notice an unexpected reaction.
How does Licorice Plus fit into overall stress support?
Use Licorice Plus as one possible part of an individualized routine, not a replacement for regular meals, sleep, movement, or professional assessment of persistent concerns. Its botanical ingredients have distinct roles, and a product aimed at cortisol metabolism is not automatically the right fit for every person experiencing stress. Your practitioner can help decide whether it belongs in your plan, how long to use it, and when to reassess your response.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
