HistaMend DAO™ by NuMedica – Advanced Diamine Oxidase Support for Histamine Intolerance
HistaMend DAO™ by NuMedica is a targeted diamine oxidase supplement designed to support histamine metabolism in the digestive tract and promote gastrointestinal symptom relief. This advanced formula combines DAO enzyme activity with antioxidant-rich pine bark extract to help degrade dietary histamine and reduce histamine intolerance symptoms. Pine bark is a potent free radical scavenger known to inhibit histamine release from mast cells and support intestinal barrier integrity by upregulating tight junction protein expression. Taking HistaMend DAO™ prior to consuming high-histamine foods and beverages helps maintain comfort and digestive balance.
Key HistaMend DAO™ Benefits
- Supports healthy histamine metabolism in the gut
- Helps reduce symptoms associated with histamine intolerance
- Promotes gastrointestinal comfort and function
- Includes pine bark extract for antioxidants and mast cell support
- Aids in maintaining intestinal barrier integrity and tight junction health
How HistaMend DAO™ Works
HistaMend DAO™ provides natural diamine oxidase (DAO) enzyme derived from porcine kidney extract, which helps break down excess histamine from food before it can cause discomfort.
- DAO Enzyme: Enhances the breakdown of dietary histamine, reducing intolerance symptoms.
- Pine Bark Extract (95% proanthocyanidins): Acts as a powerful antioxidant and supports healthy mast cell response.
- Catalase and Vitamin C: Work synergistically to protect against oxidative stress and enhance enzyme activity.
This formula is well-tolerated and designed for safe, everyday use with minimal side effects when taken as directed.
HistaMend DAO™ Is Formulated For
HistaMend DAO™ is ideal for individuals seeking safe and effective gastrointestinal symptom relief related to histamine intolerance. It’s especially suited for those who experience discomfort after consuming aged, fermented, or histamine-rich foods and who wish to support joint, bone, and skin health through balanced histamine metabolism.
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners. You may also want to explore our other GI Health and Anti-Oxidants products.
NuMedica suggests taking one capsule 1–2 times per day before a meal or as directed by your healthcare practitioner.
Servings Per Container: 60
Other Ingredients:
Digestive-resistant vegetable capsule (hydroxypropyl methylcellulose, gellan gum), microcrystalline cellulose, magnesium stearate, silicon dioxide.
Does Not Contain:
Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.
Caution:
If you are pregnant, nursing, or taking any medications, consult your healthcare practitioner before use. Keep out of reach of children.
Storage:
Keep tightly closed in a cool, dry place.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Trademark: †DAOgest is a registered trademark of BIOIBERICA, S.A.U.
Frequently Asked Questions About HistaMend DAO
What is diamine oxidase (DAO)?
Diamine oxidase (DAO) is a naturally occurring enzyme responsible for breaking down excess histamine in the digestive tract. It plays a key role in histamine metabolism and helps prevent symptoms associated with histamine intolerance—such as digestive upset, skin reactions, and headaches. HistaMend DAO™ by NuMedica provides a supplemental form of this enzyme to support balanced histamine levels and promote gastrointestinal comfort.
Where does diamine oxidase come from?
The diamine oxidase used in supplements like HistaMend DAO™ is typically derived from natural, animal-based sources such as porcine kidney extract. This source is chosen for its biological compatibility with human DAO, allowing for efficient support of histamine breakdown in the gut. Each capsule of HistaMend DAO™ provides clinically active DAO enzyme designed to assist the body in metabolizing dietary histamine.
What are the side effects of taking HistaMend DAO™?
HistaMend DAO™ is generally well-tolerated when used as directed. Since it is a naturally occurring enzyme, side effects are rare. However, some individuals may experience mild digestive discomfort or allergic reactions if sensitive to porcine-derived ingredients. As with any supplement, it’s best to consult your healthcare practitioner before use—especially if pregnant, nursing, or taking medications.
How does HistaMend DAO™ support histamine intolerance?
HistaMend DAO™ provides supplemental diamine oxidase to help the body break down histamine from foods and beverages before it causes discomfort. By supporting normal histamine metabolism in the gut, this formula can help reduce symptoms such as bloating, flushing, and sinus congestion associated with histamine sensitivity.
