DAO Enzyme by Ortho Molecular Products – Dietary Histamine and Digestive Support
DAO Enzyme by Ortho Molecular Products is a targeted diamine oxidase supplement formulated to support the normal breakdown of histamine from foods within the digestive tract. Each capsule provides 4.2 mg of DAOgest® Porcine Kidney Extract, delivering 30,000 Histamine Degrading Units (HDU) of diamine oxidase activity.
This concentrated DAO enzyme supplement is designed for adults who want additional nutritional support for healthy DAO activity and balanced histamine levels in response to dietary triggers. Taken approximately 15 minutes before a meal, the formula provides focused support where DAO is naturally active within the intestinal environment.
Key DAO Enzyme Benefits
- Supports healthy DAO enzyme activity within the digestive tract.
- Promotes balanced dietary histamine levels in response to food-related triggers.
- Provides 30,000 HDU of diamine oxidase activity per capsule.
- Supports normal histamine degradation at the intestinal barrier before absorption.
- Provides targeted gastrointestinal support in a convenient one-capsule serving.
How DAO Enzyme Works
Histamine is a naturally occurring biogenic amine found throughout the body and in a variety of foods. Aged and fermented foods, matured cheeses, cured or processed meats, fish, and fermented beverages can contain higher amounts of dietary histamine. Diamine oxidase is an important enzyme responsible for degrading histamine-containing foods. DAO is highly expressed in the intestinal mucosa and is particularly active in the small intestine, where it helps metabolize dietary histamine before absorption. DAO Enzyme supplies purified diamine oxidase through DAOgest® Porcine Kidney Extract. Providing 30,000 HDU per capsule, the formula supports normal histamine degradation in the digestive tract and promotes histamine balance support in response to dietary triggers.
Key Functional Ingredients Include:
- DAOgest® Porcine Kidney Extract: Provides a concentrated source of diamine oxidase to support the normal breakdown of histamine from foods within the gastrointestinal tract.
- Diamine Oxidase (DAO): Each capsule provides 30,000 Histamine Degrading Units to support healthy DAO enzyme activity and normal processing of food-derived histamine at the intestinal barrier.
DAO Enzyme provides a focused approach to digestive enzyme support rather than a broad-spectrum digestive enzyme blend. Because its active ingredient is derived from porcine kidney, the formula is not appropriate for individuals seeking a vegetarian or vegan supplement.
DAO Enzyme Is Formulated For
- Adults seeking nutritional support for the normal breakdown of histamine from foods.
- Individuals who want to support healthy DAO enzyme activity within the digestive tract.
- Those seeking support for balanced histamine levels in response to dietary triggers.
- People who prefer a targeted, single-active-ingredient approach to dietary histamine support.
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners, led by Carolyn Mulally BS, RN, HN-BC. You may also wish to explore our other GI Health Products, Allergy Products, and Anti Inflammation Natural Supplements collections.
Recommendation: DAO Enzyme may be appropriate for adults seeking targeted nutritional support for dietary histamine metabolism around meals. Take 1 capsule 15 minutes before a meal or as recommended by your health care professional. Consult your healthcare practitioner to determine whether supplemental DAO is appropriate for your individual dietary and wellness needs.
Serving Size: 1 Capsule
Servings Per Container: 60
Porcine Kidney Extract (DAOgest®) (providing 30,000 HDU Diamine Oxidase (DAO)) ... 4.2 mg*
* Daily Value (DV) not established.
Other Ingredients: Microcrystalline Cellulose, Delayed Release Capsule (Hypromellose, Gellan Gum), Magnesium Stearate and Silicon Dioxide.
Frequently Asked Questions About DAO Enzyme
What are the benefits of DAO Enzyme?
DAO Enzyme provides targeted support for the normal breakdown of histamine found in foods. Its primary ingredient, DAOgest® Porcine Kidney Extract, supplies 30,000 Histamine Degrading Units of diamine oxidase activity per capsule. Diamine oxidase is an enzyme active within the digestive tract that helps metabolize dietary histamine before absorption. By supplying supplemental DAO shortly before a meal, the formula supports healthy DAO enzyme activity and promotes balanced histamine levels in response to dietary triggers. It provides a focused option for adults seeking nutritional support specifically around dietary histamine metabolism.
Who should take DAO Enzyme?
DAO Enzyme may be appropriate for adults who want additional support for the normal processing of dietary histamine within the digestive tract. It may be particularly relevant for individuals working with a healthcare practitioner on a nutrition plan involving histamine-containing foods or those seeking targeted support for healthy intestinal DAO activity. Because DAOgest® is derived from porcine kidney, this product is not appropriate for vegetarian or vegan diets. Individual nutritional needs vary, so a healthcare practitioner can help determine whether supplemental DAO is appropriate and how it may fit alongside dietary strategies.
Are there any side effects of taking DAO Enzyme?
Individual responses to dietary supplements can vary. DAO Enzyme contains DAOgest® Porcine Kidney Extract along with microcrystalline cellulose, a delayed release capsule, magnesium stearate, and silicon dioxide, so the complete ingredient list should be reviewed before use if you have known sensitivities. Ortho Molecular Products advises individuals who are pregnant or nursing to consult their physician before taking the product. Following the recommended serving directions is also important. If you have questions about tolerance, dietary restrictions, medications, or whether a porcine-derived DAO supplement is appropriate for you, discuss the formula with your healthcare professional.
How does DAO Enzyme support overall health?
DAO Enzyme supports digestive wellness by assisting one of the body's normal mechanisms for processing histamine from food. Diamine oxidase is highly expressed in the intestinal mucosa and is particularly active in the small intestine, where it helps metabolize dietary histamine before absorption. Supporting normal DAO activity can complement a broader nutrition strategy focused on gastrointestinal function and balanced responses to dietary histamine. DAO Enzyme is specifically targeted to this digestive function rather than serving as a broad multinutrient formula, making it most appropriate as one component of an individualized wellness program.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
