{"num_reviews":0,"add_this":[{"service":"facebook","annotation":""},{"service":"twitter","annotation":""},{"service":"linkedin","annotation":""}],"gtin":null,"brand":{"name":"Pure Encapsulations","url":"https://covenanthealthproducts.com/pure-encapsulations/"},"id":25780,"can_purchase":true,"meta_description":"Hist Reset by Pure Encapsulations supports histamine balance, immune health, and mast cell function with quercetin, luteolin, NAC, and vitamin C.","category":["Brands/Pure Encapsulations Supplements and Vitamins","Clinic Recommended Products","Clinic Recommended Products/Allergy Products","Clinic Recommended Products/Immune Support Supplements/Allergy Immune Supporting Supplements","Clinic Recommended Products/Allergy Products/Seasonal Allergies"],"AddThisServiceButtonMeta":"","main_image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/25780/32257/hist-reset-120c-pure-encapsulations__75623.1711371269.jpg?c=1","alt":"Hist Reset 120c Pure Encapsulations"},"add_to_wishlist_url":"https://covenanthealthproducts.com/wishlist.php?action=add&product_id=25780","shipping":{"calculated":true},"custom_fields":[{"id":"151631","name":"Brand","value":"<a href='/brands/pure-encapsulations/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/pure-encapsulations_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":"151632","name":"Questions","value":"<a href='/complimentary-product-consultation/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/need_someone_to_talk_to_250px.png\"></a><div><a href=\"/need-product-help\">Talk to an Expert</a></div>"},{"id":"151633","name":"Clinic Approved","value":"Yes"},{"id":"156880","name":"Ship time","value":"Ships Same Business Day"},{"id":"172096","name":"klaviyo_tags","value":"type:supplement | goal:general-health | form:capsule"}],"sku":"HRT1","backorder_availability_prompt":"","url":"https://covenanthealthproducts.com/hist-reset-120c-pure-encapsulations","description":"<!-- Store: CHP | Product: Hist Reset | Brand: Pure Encapsulations -->\n<h2>Hist Reset by Pure Encapsulations &ndash; Histamine Support</h2>\n<p><strong>Hist Reset</strong> by <strong>Pure Encapsulations</strong> is a practitioner-formulated supplement designed to support <strong>histamine tolerance</strong>, <strong>immune health</strong>, and healthy mast cell balance. This multi-faceted formula combines flavonoids,<strong> antioxidant</strong> nutrients, and enzyme-supportive cofactors to help maintain <strong>healthy immune</strong> mediator activity and <strong>histamine metabolism</strong>.</p>\n<h3>Key Hist Reset Benefits</h3>\n<ul>\n<li>Supports <strong>healthy mast cell stabilization</strong> and immune mediator balance</li>\n<li>Promotes <strong>nasal and respiratory health</strong> during times of increased histamine exposure</li>\n<li>Helps maintain <strong>healthy histamine metabolism</strong> with targeted nutrient cofactors</li>\n<li>Provides <strong>antioxidant support</strong> from vitamin C, quercetin, luteolin, rutin, and NAC</li>\n<li>Supports individuals seeking <strong>histamine intolerance support</strong> related to dietary histamine sensitivity</li>\n</ul>\n<h3>How Hist Reset Works</h3>\n<p><strong>Hist Reset</strong> supports histamine balance through a combination of flavonoids, antioxidant nutrients, and cofactors involved in histamine breakdown. <strong>Quercetin</strong>, <strong>luteolin</strong>, and rutin help support healthy mast cell activity, while riboflavin, niacinamide, and molybdenum serve as cofactors for aldehyde dehydrogenase, an enzyme involved in the breakdown of histamine.</p>\n<h4>Key Functional Ingredients Include:</h4>\n<ul>\n<li><a title=\"Vitamin C: A Comprehensive Review of Its Role in Health, Disease Prevention, and Therapeutic Potential\" href=\"https://pubmed.ncbi.nlm.nih.gov/39942850/\" target=\"_blank\" rel=\"noopener\"><strong>Vitamin C</strong></a>: Provides antioxidant support and helps maintain healthy immune function</li>\n<li><a title=\"The Role of Quercetin, a Flavonoid in the Management of Pathogenesis Through Regulation of Oxidative Stress, Inflammation, and Biological Activities\" href=\"https://pubmed.ncbi.nlm.nih.gov/39858545/\" target=\"_blank\" rel=\"noopener\"><strong>Quercetin</strong></a>: A flavonoid that supports healthy mast cell and immune mediator balance</li>\n<li><a title=\"Exploring the Therapeutic Potential of Bromelain: Applications, Benefits, and Mechanisms\" href=\"https://pmc.ncbi.nlm.nih.gov/articles/PMC11243481/\" target=\"_blank\" rel=\"noopener\"><strong>Bromelain</strong></a>: A pineapple-derived protease that supports tissue comfort and immune function</li>\n<li><strong><a title=\"Luteolin: A promising multifunctional natural flavonoid for human diseases\" href=\"https://pubmed.ncbi.nlm.nih.gov/38666435/\" target=\"_blank\" rel=\"noopener\">Luteolin</a> and <a title=\"Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature\" href=\"https://pubmed.ncbi.nlm.nih.gov/35257898/\" target=\"_blank\" rel=\"noopener\">Rutin</a></strong>: Flavonoids that support antioxidant activity and immune balance</li>\n<li><strong><a title=\"Vitamin B2 (Riboflavin)\" href=\"https://www.ncbi.nlm.nih.gov/books/NBK525977/\" target=\"_blank\" rel=\"noopener\">Riboflavin</a>, <a title=\"Increased Dietary Niacin Intake Improves Muscle Strength, Quality, and Glucose Homeostasis in Adults over 40 Years of Age\" href=\"https://pubmed.ncbi.nlm.nih.gov/37754210/\" target=\"_blank\" rel=\"noopener\">Niacin</a>, and <a title=\"Molybdenum&rsquo;s Role as an Essential Element in Enzymes Catabolizing Redox Reactions: A Review\" href=\"https://pmc.ncbi.nlm.nih.gov/articles/PMC11275037/\" target=\"_blank\" rel=\"noopener\">Molybdenum</a></strong>: Nutrient cofactors that support healthy histamine metabolism</li>\n</ul>\n<p>Pure Encapsulations products are formulated using high-quality ingredients and are made without many common allergens, unnecessary binders, fillers, preservatives, artificial colors, sweeteners, coatings, and shellacs.</p>\n<h3>Hist Reset Is Formulated For</h3>\n<ul>\n<li>Individuals seeking <strong>histamine support supplement</strong> options for food-related histamine sensitivity</li>\n<li>Those looking to support healthy nasal, respiratory, skin, and gastrointestinal comfort</li>\n<li>People who want targeted <strong>immune mediator support</strong> from flavonoids and antioxidant nutrients</li>\n<li>Individuals following a practitioner-guided plan for <strong>mast cell support</strong> and histamine balance</li>\n</ul>\n<p><strong>Supplements support your health but do not replace a balanced diet.</strong> Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a <a title=\"Complimentary Product Consultation\" href=\"https://covenanthealthproducts.com/complimentary-product-consultation/\" target=\"_blank\" rel=\"noopener\"><strong>FREE product consultation</strong></a> with Holistic Health Partners. You may also want to explore our other <a href=\"https://covenanthealthproducts.com/clinic-recommended-products/allergy-products/food-allergies/\" target=\"_blank\" rel=\"noopener\"><strong>Food Allergies</strong></a> collection.</p>\n<p><strong>Recommendation:</strong> 2 capsules daily, between meals, or as directed by a health professional.</p>\n<p><strong>Serving Size:</strong> Two (size 0) capsules<br /><strong>Servings Per Container:</strong> 60</p>\n<div><strong>Amount Per Serving:</strong><br />Vitamin C (as ascorbic acid) ... 250 mg<br />Riboflavin ... 5 mg<br />Niacin (as niacinamide) ... 20 mg<br />Molybdenum (as molybdenum glycinate) ... 100 mcg<br />N-Acetyl-L-Cysteine ... 100 mg<br />Quercetin ... 300 mg<br />Bromelain (from pineapple stem) (2,400 GDU/gram) ... 200 mg<br />Luteolin ... 100 mg<br />Rutin ... 100 mg<br /><br /></div>\n<p><strong>Other Ingredients:</strong> vegetarian capsule (cellulose, water)</p>\n<p><strong>Does not contain:</strong> Wheat, soy, dairy, eggs, artificial colors and sweeteners, coatings and shellacs, GMOs, tree nuts, peanuts, sesame, unnecessary binders, fillers and preservatives, magnesium stearate, gluten, trans fat and hydrogenated oils.</p>\n<p><strong>Storage:</strong> Store in a cool, dry place.</p>\n<p><strong>Warnings/Cautions:</strong> Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use. Keep out of the reach of children. Use only if the safety seal is intact. Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.</p>\n<p><em>These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.</em></p>\n<p><a title=\"Product Info Sheet\" href=\"https://www.pureencapsulationspro.com/media/pdf_upload/Pure_Hist_Reset_One_Pager_No_Promo_No_Price.pdf\" target=\"_blank\" rel=\"noopener\">Click here to view Product Info Sheet</a></p>\n<p><strong>References:</strong></p>\n<ol>\n<li>Maintz L, Novak N. Am J Clin Nutr. 2007 May;85(5):1185-96.</li>\n<li>Maintz L, Yu CF, Rodr&iacute;guez E, et al. Allergy. 2011;66(7):893-902.</li>\n<li>Ayuso P, Garc&iacute;a-Mart&iacute;n E, Mart&iacute;nez C, Ag&uacute;ndez JA. Pharmacogenet Genomics. 2007;17(9):687-693.</li>\n<li>Theoharides TC, et al. Front Neurosci. 2015 Jul 3;9:225.</li>\n<li>Weng Z, et al. PLoS One. 2012;7(3):e33805.</li>\n<li>Kimata M, et al. Clin Exp Allergy. 2000 Apr;30(4):501-8.</li>\n<li>Park HH, et al. Arch Pharm Res. 2008 Oct;31(10):1303-11.</li>\n<li>Bucca C, et al. Ann Allergy. 1990 Oct;65(4):311-4.</li>\n<li>Johnston CS, et al. J Am Coll Nutr. 1996;15:586-591.</li>\n</ol>","show_backorder_message":false,"tags":[],"warranty":"","price":{"without_tax":{"formatted":"$61.00","value":61,"currency":"USD"},"tax_label":"Tax"},"default_shipping_expectation_prompt":"","detail_messages":"","availability":"Ships Same Business Day","page_title":"Hist Reset 120c | Pure Encapsulations","cart_url":"https://covenanthealthproducts.com/cart.php","show_backorder_availability_prompt":false,"max_purchase_quantity":0,"show_quantity_on_hand":true,"show_default_shipping_expectation_prompt":false,"show_quantity_on_backorder":false,"mpn":"HRT1","upc":null,"options":[{"id":44508,"type":"Configurable_PickList_Set","display_name":"Recurring Order","required":true,"state":"modifier","partial":"set-select","condition":true,"values":[{"id":48845,"label":"One Time Purchase","selected":true,"data":"One Time Purchase"},{"id":48846,"label":"Every 20 Days","selected":false,"data":"Every 20 Days"},{"id":48847,"label":"Every 30 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2021","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":153141,"name":"Brand","value":"<a href='/Ortho-Molecular-Products_c_2954.html'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/ortho-molecular-products_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":153142,"name":"How to Order","value":"<a href=\"/restricted-brands-access/\"><img class=\"lazyload\" data-sizes=\"auto\" data-src=\"/product_images/uploaded_images/register-to-purchase-button.png\" width=\"183\" height=\"32\" alt=\"Register to Purchase this product\"></a>"},{"id":153143,"name":"Registered","value":"<a href=\"tel:800-627-6518\"><img class=\"lazyload\" data-sizes=\"auto\" data-src=\"/product_images/uploaded_images/call-to-order-restricted-brands.png\" width=\"183\" height=\"32\" alt=\"Call to Purchase this product\"></a>"},{"id":153144,"name":"Questions","value":"<a href='/complimentary-product-consultation/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/need_someone_to_talk_to_250px.png\"></a><div><a href=\"/need-product-help\">Talk to an Expert</a></div>"},{"id":153145,"name":"Clinic Approved","value":"Yes"},{"id":153393,"name":"Blog Post","value":"<a href='/our-blog/ortho-molecular-product-natural-d-hist'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/Click_here_for_Blog_250px.png\"></a><a href=\"/blog\">View Blog Post</a>"},{"id":158675,"name":"Ship time","value":"Ships Same Business Day"},{"id":166071,"name":"klaviyo_tags","value":"type:supplement | goal:general-health | form:capsule"}],"num_reviews":8,"weight":{"formatted":"0.00 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120c","gift_wrapping_available":false,"min_purchase_quantity":0,"customizations":[],"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/25780/32257/hist-reset-120c-pure-encapsulations__75623.1711371269.jpg?c=1","alt":"Hist Reset 120c Pure Encapsulations"},{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/25780/51700/Hist_Reset_120c_Pure_Encapsulations_label__86433.1778029085.png?c=1","alt":"Hist Reset 120c Pure Encapsulations label"}]}
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Hist Reset 120c Pure Encapsulations

Hist Reset 120c

Pure Encapsulations

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Hist Reset by Pure Encapsulations – Histamine Support

Hist Reset by Pure Encapsulations is a practitioner-formulated supplement designed to support histamine tolerance, immune health, and healthy mast cell balance. This multi-faceted formula combines flavonoids, antioxidant nutrients, and enzyme-supportive cofactors to help maintain healthy immune mediator activity and histamine metabolism.

Key Hist Reset Benefits

  • Supports healthy mast cell stabilization and immune mediator balance
  • Promotes nasal and respiratory health during times of increased histamine exposure
  • Helps maintain healthy histamine metabolism with targeted nutrient cofactors
  • Provides antioxidant support from vitamin C, quercetin, luteolin, rutin, and NAC
  • Supports individuals seeking histamine intolerance support related to dietary histamine sensitivity

How Hist Reset Works

Hist Reset supports histamine balance through a combination of flavonoids, antioxidant nutrients, and cofactors involved in histamine breakdown. Quercetin, luteolin, and rutin help support healthy mast cell activity, while riboflavin, niacinamide, and molybdenum serve as cofactors for aldehyde dehydrogenase, an enzyme involved in the breakdown of histamine.

Key Functional Ingredients Include:

  • Vitamin C: Provides antioxidant support and helps maintain healthy immune function
  • Quercetin: A flavonoid that supports healthy mast cell and immune mediator balance
  • Bromelain: A pineapple-derived protease that supports tissue comfort and immune function
  • Luteolin and Rutin: Flavonoids that support antioxidant activity and immune balance
  • Riboflavin, Niacin, and Molybdenum: Nutrient cofactors that support healthy histamine metabolism

Pure Encapsulations products are formulated using high-quality ingredients and are made without many common allergens, unnecessary binders, fillers, preservatives, artificial colors, sweeteners, coatings, and shellacs.

Hist Reset Is Formulated For

  • Individuals seeking histamine support supplement options for food-related histamine sensitivity
  • Those looking to support healthy nasal, respiratory, skin, and gastrointestinal comfort
  • People who want targeted immune mediator support from flavonoids and antioxidant nutrients
  • Individuals following a practitioner-guided plan for mast cell support and histamine balance

Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners. You may also want to explore our other Food Allergies collection.

Recommendation: 2 capsules daily, between meals, or as directed by a health professional.

Serving Size: Two (size 0) capsules
Servings Per Container: 60

Amount Per Serving:
Vitamin C (as ascorbic acid) ... 250 mg
Riboflavin ... 5 mg
Niacin (as niacinamide) ... 20 mg
Molybdenum (as molybdenum glycinate) ... 100 mcg
N-Acetyl-L-Cysteine ... 100 mg
Quercetin ... 300 mg
Bromelain (from pineapple stem) (2,400 GDU/gram) ... 200 mg
Luteolin ... 100 mg
Rutin ... 100 mg

Other Ingredients: vegetarian capsule (cellulose, water)

Does not contain: Wheat, soy, dairy, eggs, artificial colors and sweeteners, coatings and shellacs, GMOs, tree nuts, peanuts, sesame, unnecessary binders, fillers and preservatives, magnesium stearate, gluten, trans fat and hydrogenated oils.

Storage: Store in a cool, dry place.

Warnings/Cautions: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use. Keep out of the reach of children. Use only if the safety seal is intact. Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Click here to view Product Info Sheet

References:

  1. Maintz L, Novak N. Am J Clin Nutr. 2007 May;85(5):1185-96.
  2. Maintz L, Yu CF, Rodríguez E, et al. Allergy. 2011;66(7):893-902.
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  4. Theoharides TC, et al. Front Neurosci. 2015 Jul 3;9:225.
  5. Weng Z, et al. PLoS One. 2012;7(3):e33805.
  6. Kimata M, et al. Clin Exp Allergy. 2000 Apr;30(4):501-8.
  7. Park HH, et al. Arch Pharm Res. 2008 Oct;31(10):1303-11.
  8. Bucca C, et al. Ann Allergy. 1990 Oct;65(4):311-4.
  9. Johnston CS, et al. J Am Coll Nutr. 1996;15:586-591.
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