5-MTHF ES by XYMOGEN – Bioactive Folate and Methylation Support
5-MTHF ES by XYMOGEN provides a concentrated source of biologically active folate for individuals seeking targeted methylation support, healthy cellular function, and nutritional support for cardiovascular and neurological health. Each two-capsule serving supplies 17,000 mcg DFE of folate as (6S)-5-methyltetrahydrofolic acid, glucosamine salt.
This professional formula features Quatrefolic®, a glucosamine salt form of 5-MTHF. Because 5-MTHF is an active form of folate, it provides folate in a form that can participate directly in normal folate-dependent processes rather than requiring conversion from synthetic folic acid.
Key 5-MTHF ES Benefits
- Provides 17,000 mcg DFE of bioactive folate per two-capsule serving.
- Supports normal methylation and healthy cellular energy metabolism.
- Supports the normal conversion of homocysteine to methionine.
- Promotes cardiovascular, neurological, and prenatal nutritional support.
- Supports normal cellular proliferation, including healthy red blood cell formation.
How 5-MTHF ES Works
Folate participates in numerous biochemical processes involving methylation, DNA synthesis, amino acid metabolism, and normal cellular activity. 5-MTHF ES supplies folate as 5-methyltetrahydrofolate, an active folate form that can be readily utilized in these pathways. This makes the formula a targeted option for people seeking a high-potency folate supplement without relying on synthetic folic acid. Folate also assists the normal conversion of homocysteine to methionine, supporting methylation and normal cardiovascular and neurological functions. Adequate folate is additionally important for normal cellular proliferation and healthy red blood cell formation. By delivering 5-MTHF as Quatrefolic®, this formula provides a stable, soluble form designed for effective nutritional folate support.
Key Functional Ingredients Include:
- Folate (5-MTHF): Provides an active form of folate that supports methylation, normal DNA synthesis, cellular proliferation, and healthy red blood cell formation.
- Quatrefolic®: The glucosamine salt of (6S)-5-methyltetrahydrofolic acid used in this formula to provide a stable, soluble, bioactive source of folate.
5-MTHF ES is formulated without animal products, corn, dairy, egg, fish, gluten, genetically modified ingredients, peanuts, shellfish, soy, tree nuts, wheat, or yeast, making it suitable for many individuals seeking a streamlined professional folate formula.
5-MTHF ES Is Formulated For
- Adults seeking concentrated methylfolate supplementation and healthy serum folate support.
- Individuals who want nutritional support for normal methylation and cellular processes.
- Those seeking folate support for cardiovascular and neurological wellness.
- Individuals whose healthcare practitioner recommends high-potency bioactive folate, including during preconception or prenatal nutritional planning.
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners, led by Carolyn Mulally BS, RN, HN-BC. You may also wish to explore our other Womens Pre-Natal Vitamins, Cardiovascular Supplements, and Brain Products collections.
Recommendation: 5-MTHF ES may be appropriate when a healthcare practitioner recommends a concentrated active folate formula for methylation, cellular, cardiovascular, neurological, or prenatal nutritional support. Because this product supplies a high amount of folate per serving, discuss your individual needs and appropriate intake with a qualified healthcare professional.
Serving Size: 2 Capsules
Servings Per Container: 30
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) ... 17,000 mcg DFE
Quatrefolic® is a registered trademark of Gnosis S.p.A. Produced under U.S. Patent 7,947,662.
Other Ingredients: Microcrystalline cellulose, capsule (hypromellose and water), stearic acid, magnesium stearate, and silica.
Does Not Contain: Animal products, corn, dairy, egg, fish, gluten, GMO ingredients, peanuts, shellfish, soy, tree nuts, wheat, and yeast.
Storage: Keep closed in a cool, dry place out of reach of children.
Frequently Asked Questions About 5-MTHF ES
What are the benefits of 5-MTHF ES?
5-MTHF ES provides a concentrated amount of active folate as 5-methyltetrahydrofolate. Folate supports methylation, normal cellular proliferation, DNA synthesis, and healthy red blood cell formation. It also assists the normal conversion of homocysteine to methionine and supports cardiovascular and neurological wellness. XYMOGEN uses Quatrefolic®, a glucosamine salt of 5-MTHF, to provide the folate in an active form. The formula may be useful for people whose healthcare practitioner recommends targeted, high-potency folate supplementation rather than a general multivitamin.
Who should take 5-MTHF ES?
5-MTHF ES may be considered by adults whose healthcare practitioner recommends supplemental active folate for methylation, cellular function, cardiovascular or neurological support. Folate also has important nutritional roles before and during pregnancy, so a practitioner may recommend an appropriate folate supplement as part of individualized prenatal nutrition. Because 5-MTHF ES supplies 17,000 mcg DFE of folate per two-capsule serving, it is a concentrated professional formula rather than a routine low-dose folate supplement. Consult your healthcare professional to determine whether this strength and serving amount are appropriate for your individual needs.
Are there any side effects of taking 5-MTHF ES?
Individual responses to dietary supplements can vary. XYMOGEN recommends consulting your healthcare professional before using 5-MTHF ES, and individuals taking medication should discuss potential interactions with their healthcare professional. The manufacturer's directions specify taking one to two capsules daily, or as directed by a healthcare professional. Because this formula provides a concentrated amount of active folate, following individualized professional guidance is especially appropriate. Do not use the product if the tamper seal is damaged, and discontinue use and consult your healthcare practitioner if you experience an unexpected or concerning reaction.
How does 5-MTHF ES support overall health?
Folate contributes to fundamental processes that occur throughout the body, including methylation, DNA synthesis, normal cellular proliferation, and red blood cell formation. 5-MTHF ES provides folate as active 5-MTHF, allowing it to participate directly in folate-dependent biochemical pathways. It also supports the normal conversion of homocysteine to methionine, an important component of methylation metabolism. Through these nutritional roles, adequate folate helps support normal cardiovascular, neurological, and cellular functions. 5-MTHF ES is designed for targeted folate supplementation when a higher-potency active folate formula is considered appropriate by a healthcare professional.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
