Histazyme by Amy Myers MD – Dietary Histamine Digestion Support
Histazyme capsules by Amy Myers MD provide a porcine-derived enzyme for histamine digestion around meals. Unlike a broad digestive enzyme blend, this formula focuses on diamine oxidase, the enzyme that breaks down histamine rather than proteins, fats, or carbohydrates.
This DAO enzyme supplement is designed for food-related use, with each capsule supplying 15mg of the enzyme and more than 18,000 histamine-degrading units. The 60-capsule bottle contains 60 labeled servings. Its animal-derived active ingredient is an important consideration even though the capsule shell is made with vegetable-derived hypromellose.
Key Histazyme Benefits
- Supports the enzymatic breakdown of dietary histamine, helping process this naturally occurring food component as part of digestion.
- Provides targeted enzyme activity for food-derived histamine, rather than a general blend for digesting the major nutrients in meals.
- Offers mealtime enzyme support that can complement an individualized food plan without replacing careful food choices or professional guidance.
How Histazyme Works
Histamine is a naturally occurring compound that can be present in foods, including some fermented or aged foods. Diamine oxidase helps break it down through an enzyme-driven reaction. This is different from blocking histamine receptors: the formula's purpose is to act on histamine from food within the digestive tract, not to provide an antihistamine drug effect throughout the body.
Timing matters because Histazyme is intended to accompany food exposure. Taking the capsule shortly before eating places its intended use around the meal rather than treating it like a general once-daily vitamin. The enzyme does not digest every component of a meal, and it does not make a food appropriate for someone who must avoid that food because of an allergy.
Key Functional Ingredients Include:
- Diamine Oxidase (from porcine): Breaks down histamine through an enzymatic reaction, supporting the processing of histamine encountered in food. DAO has a different job from enzymes that digest protein or starch. Its targeted role explains this formula's food-focused purpose; the porcine source also means it is unsuitable for people who avoid pork.
Histazyme Is Formulated For
- Adults seeking focused support for processing histamine from meals, with guidance on whether a DAO supplement fits their needs.
- People following a practitioner-guided food plan who want a single active enzyme rather than a broad digestive enzyme formula.
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners, led by Carolyn Mulally BS, RN, HN-BC. You may also wish to explore our other GI Digestion/Enzyme Supplements, GI Health Supplements, and Amy Myers MD collections.
Recommendation: Take 1 capsule no more than 15 minutes before the consumption of histamine-rich foods, or as recommended by your healthcare practitioner.
Serving Size: 1 Capsule
Servings Per Container: 60
Diamine Oxidase (from porcine) ... 15mg (>18,000 HDU) **
** Daily Value not established.
Other Ingredients: Microcrystalline cellulose, hypromellose (vegetable capsule), L-leucine, silica.
Frequently Asked Questions About Histazyme
What are the benefits of Histazyme?
Histazyme provides diamine oxidase, an enzyme that breaks down histamine from food. Each capsule contains 15mg of porcine-derived DAO, supplying more than 18,000 histamine-degrading units. Its focus is dietary histamine rather than the proteins, fats, and carbohydrates targeted by broad digestive enzyme blends. This makes its role specific to mealtime histamine processing. It complements an individualized food plan, but it does not replace food avoidance when an allergy is present.
Who should take Histazyme?
Histazyme is intended for adults considering targeted support for processing histamine from meals. A healthcare practitioner can help decide whether its single-enzyme approach fits your food plan and digestive needs. The active ingredient comes from pigs, so it is not suitable for someone allergic to pork or avoiding pork for dietary or religious reasons. Although the shell is a vegetable capsule, the finished supplement is not vegetarian. Pregnant or nursing individuals should consult their healthcare practitioner before use.
Are there any side effects of taking Histazyme?
Consult your healthcare practitioner before use, especially if you are pregnant or nursing. Keep out of reach of children. Avoid if allergic to pork or any other ingredient. Histazyme is NOT EFFECTIVE for symptoms of immune-related food allergies, such as peanuts, shellfish, etc., or for gluten intolerance due to sensitivity or celiac disease. Because Histazyme contains porcine-derived DAO and several capsule ingredients, review the full ingredient list if you have sensitivities. Stop use and seek medical advice if an unwanted reaction occurs. It does not replace prescribed allergy medication or emergency care.
How does Histazyme support overall health?
Histazyme has a focused digestive role: its DAO enzyme helps break down food-derived histamine. That role is local to digestion, not a whole-body antihistamine effect or a substitute for a balanced diet. The manufacturer directs taking 1 capsule no more than 15 minutes before histamine-rich foods, unless your healthcare practitioner recommends otherwise. Matching the supplement to the meal and to an appropriate food plan is more useful than expecting it to address every digestive concern.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
