Folate 5,000 Plus by Pure Encapsulations® – Activated Folate and Methylation Support
Folate 5,000 Plus by Pure Encapsulations is a high-potency activated folate supplement formulated for adults seeking practitioner-directed support for cellular function, nervous system health, and healthy methylation. Each vegetarian capsule combines biologically active folate with activated forms of vitamins B6 and B12, allowing these nutrients to participate efficiently in important biochemical processes.
This specialized methylation support formula may be particularly appropriate for individuals who have difficulty converting conventional folic acid into a usable form. It also supports normal neurotransmitter production, healthy DNA formation, energy metabolism, and overall cellular wellness.
Key Folate 5,000 Plus Benefits
- Provides 5,000 mcg of 5-MTHF folate, a biologically active form that can be used without multiple conversion steps.
- Supports healthy methylation, cellular function, and normal genetic expression.
- Promotes healthy nervous system activity and neurotransmitter support.
- Combines activated folate with vitamins B6 and B12 for complementary nutritional support.
How Folate 5,000 Plus Works
Folate participates in methylation, a network of biochemical reactions that helps regulate cellular activity, DNA production, neurotransmitter formation, hormone metabolism, and energy pathways. Conventional folic acid must pass through several enzymatic conversion steps before the body can use it. Folate 5,000 Plus supplies methyltetrahydrofolate, an active vitamin B9 form that bypasses key activation steps involving the DHFR and MTHFR enzymes.
The formula also provides methylcobalamin and pyridoxal 5’ phosphate, the activated forms of vitamins B12 and B6. Together, these nutrients serve as complementary cofactors in methyl-group transfer and amino-acid metabolism. This coordinated combination supports healthy blood cells, normal neurological function, cellular maintenance, and balanced production of chemical messengers used by the nervous system.
Key Functional Ingredients Include:
- Methyltetrahydrofolate: Provides directly usable folate to support healthy DNA synthesis, methylation, cellular renewal, and normal nervous system function.
- Pyridoxal 5’ phosphate: The activated form of vitamin B6 supports amino-acid metabolism, neurotransmitter production, and normal energy pathways.
- Methylcobalamin: An active form of vitamin B12 that supports methylation, neuronal health, red blood cell formation, and cellular energy metabolism.
This high-potency folate formula is made with vegan ingredients and a vegetarian capsule. Pure Encapsulations formulates it without gluten, wheat, soy, dairy, eggs, peanuts, tree nuts, sesame, artificial colors, artificial sweeteners, unnecessary preservatives, magnesium stearate, or genetically modified ingredients.
Folate 5,000 Plus Is Formulated For
- Adults seeking professionally guided cellular health support from activated B vitamins.
- Individuals who may not efficiently convert supplemental folic acid into its active form.
- Those looking to support methylation, nervous system function, positive mood, or normal energy metabolism.
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners, led by Carolyn Mulally BS, RN, HN-BC. You may also wish to explore our other Brain Products, Mood Support Supplements, and Cardiovascular Supplements collections.
Recommendation: As a dietary supplement, take 1 capsule daily, with a meal or as directed by a health professional. Because this formula supplies a concentrated amount of activated folate, it should be selected with guidance from a qualified healthcare practitioner who can evaluate individual nutritional needs, medications, and health considerations.
Serving Size: 1 vegetarian capsule
Servings Per Container: 60
Vitamin B6 (as pyridoxal 5’ phosphate (activated B6)) ... 25 mg
Folate ... 8,333 mcg DFE (5,000 mcg L-5-MTHF)
Vitamin B12 (as methylcobalamin) ... 1,000 mcg
Metafolin® is a registered trademark of Merck KGaA, Darmstadt, Germany.
Other Ingredients: hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water)
Does Not Contain: Wheat, soy, dairy, eggs, tree nuts, peanuts, sesame, gluten, GMOs, artificial colors and sweeteners, coatings and shellacs, unnecessary binders, fillers and preservatives, magnesium stearate, trans fat, or hydrogenated oils.
Storage: Store in a cool, dry place.
Warnings/Cautions: Use only under medical supervision. If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.
Frequently Asked Questions About Folate 5,000 Plus
What are the main health benefits of Folate 5,000 Plus by Pure Encapsulations?
Folate 5,000 Plus by Pure Encapsulations is designed to support healthy methylation, cellular function, and nervous system health by providing folate in its biologically active form. It also includes activated vitamins B6 and B12, which work alongside folate to support normal DNA synthesis, red blood cell production, and energy metabolism. This combination helps promote healthy cognitive function, cardiovascular wellness, and overall cellular health while providing nutrients that are readily available for the body to use.
How does Folate 5,000 Plus by Pure Encapsulations work in the body?
Folate 5,000 Plus works by supplying L-5-methyltetrahydrofolate (5-MTHF), the active form of folate that the body can use without requiring conversion from folic acid. This active folate participates in methylation, a natural process involved in DNA production, amino acid metabolism, neurotransmitter synthesis, and healthy cellular function. Activated vitamin B6 and methylcobalamin, a form of vitamin B12, complement folate by serving as important cofactors that support nutrient utilization, healthy nerve function, and normal homocysteine metabolism.
Who should consider taking Folate 5,000 Plus by Pure Encapsulations?
Folate 5,000 Plus may be appropriate for adults seeking targeted nutritional support for healthy methylation, nervous system function, or cellular wellness. Healthcare practitioners may recommend it for individuals who prefer an active form of folate instead of folic acid or who have increased nutritional needs for activated B vitamins. Because the formula provides a high amount of active folate, it is best used under the guidance of a qualified healthcare professional who can determine whether it is appropriate for an individual's nutritional needs and health goals.
Are there any side effects associated with Folate 5,000 Plus by Pure Encapsulations?
Individual responses to Folate 5,000 Plus can vary, and supplements containing high-potency B vitamins may not be appropriate for everyone. Because this formula supplies a concentrated amount of active folate along with activated vitamins B6 and B12, it should be used only under medical supervision. Individuals who are pregnant or lactating, have a health condition, or take medication should consult their healthcare professional before use. Following practitioner guidance and the recommended serving can help support appropriate use.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
