AdvaClear by Metagenics – Daily Liver and Detoxification Support
AdvaClear by Metagenics combines vitamins, minerals, amino acid nutrients, and plant extracts for daily detoxification support. Rather than relying on a single botanical, this capsule formula brings together nutritional support for the liver's normal processing pathways, antioxidant defenses, and methylation. It offers a practical option for adults whose healthcare practitioner recommends a multi-ingredient approach to liver wellness. Both the 42-capsule and 126-capsule bottles provide the same two-capsule serving, so the choice is about supply rather than a different strength.*
Key AdvaClear Benefits
- Provides liver health support through a combination designed for normal phase I and phase II detoxification pathways.*
- Offers antioxidant support from vitamins C and E alongside NAC and botanical ingredients, complementing the body's own cellular defenses.*
- Includes methylcobalamin and L-5-methyltetrahydrofolate for methylation support, together with other B vitamins involved in everyday nutrient metabolism.*
How AdvaClear Works
The liver processes compounds through linked enzyme systems. Phase I changes their chemical structure, while phase II attaches other molecules to help prepare them for elimination. AdvaClear's approach to phase I and phase II support pairs nutritional cofactors with botanical ingredients rather than treating detoxification as a one-time flush. Its B vitamins participate in normal metabolic reactions, while its antioxidant components complement cellular protection. These are ongoing physiological processes supported by adequate nutrition, not a reason to fast or replace meals with supplements.*
Key Functional Ingredients Include:
- N-Acetyl-L-Cysteine: Supplies a precursor to cysteine, a building block used to make glutathione. This explains its place in nutritional antioxidant support without equating this blend with higher-dose NAC regimens.*
- Artichoke, watercress, and silymarin: Provide the formula's botanical liver support component; silymarin comes from milk thistle seed extract.*
- Folate and vitamin B12: Supply L-5-methyltetrahydrofolate and methylcobalamin, forms involved in normal methylation pathways.*
- Green tea and pomegranate extracts: Add standardized plant compounds, with the green tea extract specifying both catechins and EGCG.*
The vegetarian capsules use hydroxypropylmethylcellulose. Decaffeinated green tea does not mean caffeine-free: the label specifies no more than 4% caffeine in that extract. Review the complete ingredient list, especially when combining AdvaClear with a multivitamin or other botanical products.
AdvaClear Is Formulated For
- Adults seeking practitioner-guided daily nutritional support for normal liver function.*
- People who prefer several complementary detoxification-support nutrients in one capsule formula.*
- Adults comparing bottle sizes while keeping the same serving and ingredient amounts.
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners, led by Carolyn Mulally BS, RN, HN-BC. You may also wish to explore our other Detox Products, Anti-Oxidants Supplements, and NAC and Glutathione collections.
Recommendation: Take two capsules once daily or as directed by your healthcare practitioner.
Serving Size: 2 Capsules†
Servings Per Container: 21 (42 capsules); 63 (126 capsules)
Vitamin A (from mixed carotenoids†† and retinyl palmitate) ... 750 mcg
Vitamin C (as ascorbic acid) ... 133 mg
Vitamin D (as cholecalciferol) ... 0.8 mcg (33 IU)
Vitamin E (as d-alpha tocopheryl succinate) ... 44.6 mg
Thiamin (as thiamin mononitrate) ... 10 mg
Riboflavin ... 5 mg
Niacin (as niacinamide and niacin) ... 23.3 mg
Vitamin B6 (as pyridoxine HCl) ... 16.66 mg
Folate (as calcium L-5-methyltetrahydrofolate) ... 445 mcg DFE
Vitamin B12 (as methylcobalamin) ... 33.4 mcg
Biotin ... 66 mcg
Pantothenic Acid (as calcium D-pantothenate) ... 33.3 mg
Zinc (as zinc citrate) ... 6.5 mg
Selenium (as selenomethionine) ... 50 mcg
Copper (as copper citrate) ... 0.66 mg
Manganese (as manganese citrate) ... 1.66 mg
Molybdenum (as molybdenum aspartate complex) ... 66 mcg
Sodium (as sodium sulfate) ... 40 mg
Artichoke (Cynara scolymus) Leaf Extract (containing cynarin and chlorogenic acid) ... 167 mg
Watercress (Nasturtium officinale) Aerial Parts 4:1 Extract ... 133 mg
Taurine ... 117 mg
Sodium Sulfate ... 100 mg
Pomegranate (Punica granatum L.) Whole Fruit Extract [standardized to 45.8 mg gallic acid equivalent (GAE)] ... 87.5 mg
N-Acetyl-L-Cysteine ... 67 mg
Decaffeinated‡ Green Tea (Camellia sinensis) Leaf Extract [standardized to 60% (33.6 mg) catechins and 40% (22.4 mg) epigallocatechin gallate (EGCG)] ... 56 mg
Silymarin [from milk thistle (Silybum marianum) seed extract] ... 50 mg
**Daily Value not established.
†Vegetarian capsule
††Betatene® mixed carotenoids.
‡Contains no more than 4% caffeine.
Other Ingredients: Capsule (hydroxypropylmethylcellulose), microcrystalline cellulose, magnesium stearate (vegetable), and silicon dioxide.
Storage: Keep tightly closed in a cool, dry place.
Frequently Asked Questions About AdvaClear
What are the main benefits of AdvaClear?
AdvaClear supports normal liver detoxification pathways and provides antioxidant and methylation-related nutrients in one formula. Its combination includes B vitamins, NAC, artichoke, watercress, and milk thistle-derived silymarin, alongside other vitamins, minerals, and plant extracts. The goal is daily nutritional support rather than a rapid cleanse. Your practitioner can help decide whether this combination is appropriate for your diet, existing supplements, and health priorities.*
Who may consider AdvaClear, and which size should they choose?
Adults looking for practitioner-guided support for normal liver function may consider AdvaClear. The 42-capsule bottle supplies 21 servings and the 126-capsule bottle supplies 63 servings; both use the same two-capsule serving. Neither size is a stronger formula. Review your current multivitamin and other supplements before starting, since nutrients may overlap. If you are pregnant, nursing, or taking medication, consult your healthcare practitioner before use.*
Can AdvaClear cause side effects or interact with medications?
Individual tolerance varies, and a combination of botanicals, vitamins, and NAC may cause digestive discomfort or a reaction in someone sensitive to an ingredient. Stop use and seek professional advice if an unexpected reaction occurs. The green tea extract is decaffeinated but not caffeine-free. Follow the label’s pregnancy, nursing, medication, and vitamin A warnings, and have your practitioner review your full supplement list rather than assuming botanical ingredients are interaction-free.
How does AdvaClear fit into an overall wellness routine?
Use AdvaClear as directed alongside a balanced diet and the habits your healthcare practitioner recommends. Adequate nutrition supports the liver’s ongoing work; this product does not replace meals or compensate for harmful exposures. Take two capsules once daily unless your practitioner directs otherwise. Keep the bottle tightly closed in a cool, dry place. Discuss your goals and review continued use with your practitioner instead of increasing the dose on your own.*
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
