{"num_reviews":21,"url":"https://covenanthealthproducts.com/kavinace-dietary-supplement-60-capsules-by-neuroscience","add_this":[{"service":"facebook","annotation":""},{"service":"twitter","annotation":""},{"service":"linkedin","annotation":""}],"gtin":"","max_purchase_quantity":0,"brand":{"name":"NeuroScience","url":"https://covenanthealthproducts.com/neuroscience/"},"id":"20151","can_purchase":false,"meta_description":"Kavinace 60c by NeuroScience Fast and Free Shipping","category":[],"meta_keywords":"","AddThisServiceButtonMeta":"","images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/20151/23820/kavinace_60c__56045.1638816940.jpg?c=1","alt":"Kavinace 60c by NeuroScience"}],"main_image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/20151/23820/kavinace_60c__56045.1638816940.jpg?c=1","alt":"Kavinace 60c by NeuroScience"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=20151","shipping":[],"custom_fields":[{"id":"111771","name":"Brand","value":"<a href='/Neuroscience_c_2478.html'><img src=\"https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/neuroscience_278x90.png\"></a>"},{"id":"111772","name":"Questions","value":"<a href=\"https://covenanthealthproducts.com/need-product-help\"><strong>Questions About this Product?</strong></a>"}],"sku":"NS0014-NA","description":"<div id=\"description\"><h3>Kavinace 60c by NeuroScience</h3><div>Contains a blend of ingredients involved in the synthesis and activity of GABA, a neurotransmitter important for sleep*</div><div><br></div><div>GABA is the primary inhibitory neurotransmitter in the brain, meaning its central role is to balance excitability of neurons (1). Because of its function, GABA is important for promoting sleep, calm, and managing stress (2-4). Stress is thought to alter GABA synthesis and activity by affecting the expression of GABA-synthesizing enzymes and receptors (5).</div><div><br></div><div>Ingredients such as taurine and vitamin B6 are important for glutamate-GABA balance.* High glutamate can damage neurons, alter cellular homeostasis, and cause mitochondrial dysfunction, which can ultimately lead to cell death (6). Taurine demonstrates GABA-A agonist activity and protects neurons and mitochondria against glutamate-induced damage (6, 7).* Active form of vitamin B6 is important for the synthesis of GABA as it is a required cofactor for glutamate decarboxylase, the enzyme responsible for converting glutamate to GABA (8-10).*</div><div><br></div><div>References:</div><div><br></div><div>1. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.</div><div>2. Mohler H. Neuropharmacology. 2012;62(1):42-53.</div><div>3. Saper C, et al. Nature. 2005;437(7063):1257-63.</div><div>4. Mody I and Maguire J. Front Cell Neurosci. 2012;6:4.</div><div>5. Maguire J. Front Cell Neurosci. 2014;8:157.</div><div>6. Ye H, et al. Can J Neurol Sci. 2013;40(5):628-34.</div><div>7. Kletke O, et al. PLoS One. 2013;8(4):e61733.</div><div>8. Rowley N, et al. Neurochem Int. 2012;61(4):546-58.</div><div>9. Martin D. Cell Mol Neurobiol. 1987;7(3):237-53.</div><div>10. Mukherjee T, et al. Biochim Biophys Acta. 2011;1814(11):1585-96.</div><div><br></div><div>Recommendation:</div><div>Take 1-2 capsules one to two times daily or as directed by your healthcare provider. Suggested at bedtime.</div><div><br></div><div>If you are pregnant or nursing, consult your healthcare provider before use.</div><div><br></div><div>Serving Size: 2 Capsules</div><div>Servings Per Container: 30</div><div><br></div><div>Amount Per Serving:</div><div>Vitamin B6 ... 2mg</div><div>(as pyridoxal 5-phosphate)</div><div>Proprietary Blend ... 950mg</div><div>Taurine and 4-amino-3-phenylbutyric acid HCl</div><div><br></div><div>Other Ingredients: Microcrystalline cellulose, Vegetable capsule (Hypromellose, water), and Magnesium stearate (vegetable source).</div><div><br></div> </div>","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$50.00","value":50,"currency":"USD"},"tax_label":"Tax"},"detail_messages":"","availability":"This product is no longer available.","page_title":"Kavinace 60c by NeuroScience","mpn":"2057","upc":null,"options":[{"id":38971,"type":"Configurable_PickList_Set","display_name":"Recurring Order","required":true,"condition":false,"state":"modifier","values":[{"label":"One Time Purchase","id":48845,"data":"One Time Purchase","selected":true},{"label":"Every 20 Days","id":48846,"data":"Every 20 Days","selected":false},{"label":"Every 30 Days","id":48847,"data":"Every 30 Days","selected":false},{"label":"Every 40 Days","id":48848,"data":"Every 40 Days","selected":false},{"label":"Every 45 Days","id":159647,"data":"Every 45 Days","selected":false},{"label":"Every 60 Days","id":48849,"data":"Every 60 Days","selected":false},{"label":"Every 90 Days","id":48850,"data":"Every 90 Days","selected":false},{"label":"Every 120 Days","id":48851,"data":"Every 120 Days","selected":false},{"label":"Every 180 Days","id":48852,"data":"Every 180 Days","selected":false}],"partial":"set-select"}],"related_products":[{"id":25524,"sku":"NEU-NE2053","name":"Kavinace OS 60c","url":"https://covenanthealthproducts.com/kavinace-os-60c-by-neuroscience","availability":"Usually Ships in 48 to 72 Hours","rating":0,"brand":{"name":"NeuroScience"},"category":["Brands/Neuroscience","Clinic Recommended Products","Clinic Recommended Products/Sleep Supplements"],"summary":"Kavinace OS 60c by NeuroScienceKavinace OS is a scientifically formulated blend of ingredients designed to promote restful sleep and address common disruptors of a healthy sleep-wake cycle. 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Sadly, the product didn&#039;&#039;t seem to help. Didn&#039;&#039;t relax or sleep better, and it seemed to cause heart palpitations. Just not the right formula for me. ","date":"Mar 20, 2015"},{"name":"TRACY","rating":"5","title":"CSR","text":"Wonderful","date":"Mar 08, 2015"},{"name":"Apricot","rating":"5","title":"Works Well","text":"My integrative medicine doctor recommends this for sleep. Usually it works well. ","date":"Jan 15, 2015"},{"name":"mike wallace","rating":"5","title":"Fantastic Product","text":"Great Product....it helps a lot !!!!!","date":"Jan 12, 2015"},{"name":"miranda","rating":"5","title":"customer","text":"I have been using this product for several months in an effort to reduce my prescription anti-anxiety medication. It is is a fantastic supplement--much more effective than GABA. I take up to 4-6 capsules/day and sleep much better. 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Highly recommend.","date":"Dec 17, 2014"},{"name":"Eileen","rating":"2","title":"title of what?","text":"I have trouble staying asleep and decided to give Kavinace a try. At times it may have helped some, but it&#039;&#039;s hard to tell. Results weren&#039;&#039;t consistent. Even without any sort of help my sleep is not consistent. I am not currently taking Kavinace. This isn&#039;&#039;t to say that it won&#039;&#039;t be what some people need. Different strokes for different folks. Sorry.","date":"Dec 15, 2014"}]},"bulk_discount_rates":[],"title":"Kavinace 60c","gift_wrapping_available":false,"min_purchase_quantity":1}

Kavinace 60c

NeuroScience

$50.00
(21 reviews) Write a Review
SKU:
NS0014-NA
Availability:
This product is no longer available.
Minimum Purchase:
1 unit
Brand:

Kavinace 60c by NeuroScience

Contains a blend of ingredients involved in the synthesis and activity of GABA, a neurotransmitter important for sleep*

GABA is the primary inhibitory neurotransmitter in the brain, meaning its central role is to balance excitability of neurons (1). Because of its function, GABA is important for promoting sleep, calm, and managing stress (2-4). Stress is thought to alter GABA synthesis and activity by affecting the expression of GABA-synthesizing enzymes and receptors (5).

Ingredients such as taurine and vitamin B6 are important for glutamate-GABA balance.* High glutamate can damage neurons, alter cellular homeostasis, and cause mitochondrial dysfunction, which can ultimately lead to cell death (6). Taurine demonstrates GABA-A agonist activity and protects neurons and mitochondria against glutamate-induced damage (6, 7).* Active form of vitamin B6 is important for the synthesis of GABA as it is a required cofactor for glutamate decarboxylase, the enzyme responsible for converting glutamate to GABA (8-10).*

References:

1. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.
2. Mohler H. Neuropharmacology. 2012;62(1):42-53.
3. Saper C, et al. Nature. 2005;437(7063):1257-63.
4. Mody I and Maguire J. Front Cell Neurosci. 2012;6:4.
5. Maguire J. Front Cell Neurosci. 2014;8:157.
6. Ye H, et al. Can J Neurol Sci. 2013;40(5):628-34.
7. Kletke O, et al. PLoS One. 2013;8(4):e61733.
8. Rowley N, et al. Neurochem Int. 2012;61(4):546-58.
9. Martin D. Cell Mol Neurobiol. 1987;7(3):237-53.
10. Mukherjee T, et al. Biochim Biophys Acta. 2011;1814(11):1585-96.

Recommendation:
Take 1-2 capsules one to two times daily or as directed by your healthcare provider. Suggested at bedtime.

If you are pregnant or nursing, consult your healthcare provider before use.

Serving Size: 2 Capsules
Servings Per Container: 30

Amount Per Serving:
Vitamin B6 ... 2mg
(as pyridoxal 5-phosphate)
Proprietary Blend ... 950mg
Taurine and 4-amino-3-phenylbutyric acid HCl

Other Ingredients: Microcrystalline cellulose, Vegetable capsule (Hypromellose, water), and Magnesium stearate (vegetable source).

21 Reviews Hide Reviews Show Reviews

  • 1
    Didn''t work for me

    Posted by Jeanine on Mar 20, 2015

    Customer service from Covenant was terrific! Sadly, the product didn''t seem to help. Didn''t relax or sleep better, and it seemed to cause heart palpitations. Just not the right formula for me.

  • 5
    CSR

    Posted by TRACY on Mar 08, 2015

    Wonderful

  • 5
    Works Well

    Posted by Apricot on Jan 15, 2015

    My integrative medicine doctor recommends this for sleep. Usually it works well.

  • 5
    Fantastic Product

    Posted by mike wallace on Jan 12, 2015

    Great Product....it helps a lot !!!!!

  • 5
    customer

    Posted by miranda on Jan 06, 2015

    I have been using this product for several months in an effort to reduce my prescription anti-anxiety medication. It is is a fantastic supplement--much more effective than GABA. I take up to 4-6 capsules/day and sleep much better. I have run out twice, and I can definitely tell a difference!

  • 5
    Kavinace 60C Review

    Posted by Sue Carleton on Dec 19, 2014

    Just started taking this supplement. The pricing was the least expensive on the web. Thanks

  • 5
    Great product

    Posted by Shirley on Dec 18, 2014

    Kavinace is great and helps me sleep. Third party verified ingredients, I try not to take too often as I feel it loses effectiveness, but for occasional use, it''s great.

  • 5
    Kavinace

    Posted by Karen on Dec 17, 2014

    My naturopathic Dr. recommended this product to me for my sleeping problems. Have found Kavinace to be very helpful with this previously ongoing issue. A good night''s sleep and waking feeling refreshed are the great benefits of taking this product regularly. Highly recommend.

  • 2
    title of what?

    Posted by Eileen on Dec 15, 2014

    I have trouble staying asleep and decided to give Kavinace a try. At times it may have helped some, but it''s hard to tell. Results weren''t consistent. Even without any sort of help my sleep is not consistent. I am not currently taking Kavinace. This isn''t to say that it won''t be what some people need. Different strokes for different folks. Sorry.