{"num_reviews":21,"url":"https://covenanthealthproducts.com/kavinace-dietary-supplement-60-capsules-by-neuroscience","add_this":[{"service":"facebook","annotation":""},{"service":"twitter","annotation":""},{"service":"linkedin","annotation":""}],"gtin":null,"max_purchase_quantity":0,"brand":{"name":"NeuroScience","url":"https://covenanthealthproducts.com/neuroscience/"},"id":20151,"can_purchase":false,"meta_description":"Kavinace 60c by NeuroScience Fast and Free Shipping","category":[],"meta_keywords":"","AddThisServiceButtonMeta":"","images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/20151/23820/kavinace_60c__56045.1638816940.jpg?c=1","alt":"Kavinace 60c by NeuroScience"}],"main_image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/20151/23820/kavinace_60c__56045.1638816940.jpg?c=1","alt":"Kavinace 60c by NeuroScience"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=20151","shipping":[],"custom_fields":[{"id":"140288","name":"Brand","value":"<a href='/Neuroscience_c_2478.html'><img src=\"https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/neuroscience_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":"140289","name":"Questions","value":"<a href=\"https://covenanthealthproducts.com/need-product-help\"><strong>Questions About this Product?</strong></a>"}],"sku":"NS0014-NA","description":"<div id=\"description\"><h3>Kavinace 60c by NeuroScience</h3><div>Contains a blend of ingredients involved in the synthesis and activity of GABA, a neurotransmitter important for sleep*</div><div><br></div><div>GABA is the primary inhibitory neurotransmitter in the brain, meaning its central role is to balance excitability of neurons (1). Because of its function, GABA is important for promoting sleep, calm, and managing stress (2-4). Stress is thought to alter GABA synthesis and activity by affecting the expression of GABA-synthesizing enzymes and receptors (5).</div><div><br></div><div>Ingredients such as taurine and vitamin B6 are important for glutamate-GABA balance.* High glutamate can damage neurons, alter cellular homeostasis, and cause mitochondrial dysfunction, which can ultimately lead to cell death (6). Taurine demonstrates GABA-A agonist activity and protects neurons and mitochondria against glutamate-induced damage (6, 7).* Active form of vitamin B6 is important for the synthesis of GABA as it is a required cofactor for glutamate decarboxylase, the enzyme responsible for converting glutamate to GABA (8-10).*</div><div><br></div><div>References:</div><div><br></div><div>1. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.</div><div>2. Mohler H. Neuropharmacology. 2012;62(1):42-53.</div><div>3. Saper C, et al. Nature. 2005;437(7063):1257-63.</div><div>4. Mody I and Maguire J. Front Cell Neurosci. 2012;6:4.</div><div>5. Maguire J. Front Cell Neurosci. 2014;8:157.</div><div>6. Ye H, et al. Can J Neurol Sci. 2013;40(5):628-34.</div><div>7. Kletke O, et al. PLoS One. 2013;8(4):e61733.</div><div>8. Rowley N, et al. Neurochem Int. 2012;61(4):546-58.</div><div>9. Martin D. Cell Mol Neurobiol. 1987;7(3):237-53.</div><div>10. Mukherjee T, et al. Biochim Biophys Acta. 2011;1814(11):1585-96.</div><div><br></div><div>Recommendation:</div><div>Take 1-2 capsules one to two times daily or as directed by your healthcare provider. Suggested at bedtime.</div><div><br></div><div>If you are pregnant or nursing, consult your healthcare provider before use.</div><div><br></div><div>Serving Size: 2 Capsules</div><div>Servings Per Container: 30</div><div><br></div><div>Amount Per Serving:</div><div>Vitamin B6 ... 2mg</div><div>(as pyridoxal 5-phosphate)</div><div>Proprietary Blend ... 950mg</div><div>Taurine and 4-amino-3-phenylbutyric acid HCl</div><div><br></div><div>Other Ingredients: Microcrystalline cellulose, Vegetable capsule (Hypromellose, water), and Magnesium stearate (vegetable source).</div><div><br></div> </div>","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$50.00","value":50,"currency":"USD"},"tax_label":"Tax"},"detail_messages":"","availability":"This product is no longer available","page_title":"Kavinace 60c by NeuroScience","mpn":"2057","upc":null,"options":[{"id":38971,"type":"Configurable_PickList_Set","display_name":"Recurring Order","required":true,"condition":false,"state":"modifier","values":[{"label":"One Time Purchase","id":48845,"data":"One Time Purchase","selected":true},{"label":"Every 20 Days","id":48846,"data":"Every 20 Days","selected":false},{"label":"Every 30 Days","id":48847,"data":"Every 30 Days","selected":false},{"label":"Every 40 Days","id":48848,"data":"Every 40 Days","selected":false},{"label":"Every 45 Days","id":159647,"data":"Every 45 Days","selected":false},{"label":"Every 60 Days","id":48849,"data":"Every 60 Days","selected":false},{"label":"Every 90 Days","id":48850,"data":"Every 90 Days","selected":false},{"label":"Every 120 Days","id":48851,"data":"Every 120 Days","selected":false},{"label":"Every 180 Days","id":48852,"data":"Every 180 Days","selected":false}],"partial":"set-select"}],"related_products":[{"id":25524,"sku":"NEU-NE2053","name":"Kavinace OS 60c","url":"https://covenanthealthproducts.com/kavinace-os-60c-by-neuroscience","availability":"Usually Ships in 48 to 72 Hours","rating":0,"brand":{"name":"NeuroScience"},"category":["Brands/Neuroscience Supplements and Vitamins"],"summary":"Kavinace OS 60c by NeuroScienceKavinace OS is a scientifically formulated blend of ingredients designed to promote restful sleep and address common disruptors of a healthy sleep-wake cycle. It...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/25524/28638/kavinace-os-60c__59590.1638817153.jpg?c=1","alt":"Kavinace OS 60c by NeuroScience"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/25524/28638/kavinace-os-60c__59590.1638817153.jpg?c=1","alt":"Kavinace OS 60c by NeuroScience"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":140334,"name":"Brand","value":"<a href='/Neuroscience_c_2478.html'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/neuroscience_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":140335,"name":"Questions","value":"<a href=\"https://covenanthealthproducts.com/need-product-help\"><strong>Questions About this Product?</strong></a>"}],"num_reviews":0,"weight":{"formatted":"0.00 Ounces","value":0},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$51.00","value":51},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=25524"},{"id":18247,"sku":"NS0015-NA","name":"Kavinace 120c","url":"https://covenanthealthproducts.com/kavinace-120-capsules-by-neuroscience","availability":"This product is no longer available","rating":5,"brand":{"name":"NeuroScience"},"category":[],"summary":"Kavinace 120c by NeuroScienceContains a blend of ingredients involved in the synthesis and activity of GABA, a neurotransmitter important for sleep*GABA is the primary inhibitory neurotransmitter in...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/18247/21789/kavinace_120c__20259.1638816848.jpg?c=1","alt":"Kavinace 120c by NeuroScience"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/18247/21789/kavinace_120c__20259.1638816848.jpg?c=1","alt":"Kavinace 120c by NeuroScience"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":false,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":140286,"name":"Brand","value":"<a href='/Neuroscience_c_2478.html'><img src=\"https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/neuroscience_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":140287,"name":"Questions","value":"<a href=\"https://covenanthealthproducts.com/need-product-help\"><strong>Questions About this Product?</strong></a>"}],"num_reviews":10,"weight":{"formatted":"0.00 Ounces","value":0},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$88.00","value":88},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=18247"},{"id":18299,"sku":"NS0016-NA","name":"Kavinace Ultra PM 30c","url":"https://covenanthealthproducts.com/kavinace-ultra-pm-30-capsules-by-neuroscience","availability":"This product is no longer available","rating":5,"brand":{"name":"NeuroScience"},"category":[],"summary":"Kavinace Ultra PM 30c by NeuroScienceBlend of ingredients shown to improve onset and quality of sleep*Kavinace Ultra PM provides the strongest sleep support among Kavinace products**GABA is the...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/18299/21876/kavinace_ultra_pm_30c__41576.1638816852.jpg?c=1","alt":"Kavinace Ultra PM 30c by NeuroScience"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/18299/21876/kavinace_ultra_pm_30c__41576.1638816852.jpg?c=1","alt":"Kavinace Ultra PM 30c by NeuroScience"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":false,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":140292,"name":"Brand","value":"<a href='/Neuroscience_c_2478.html'><img src=\"https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/neuroscience_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":140293,"name":"Questions","value":"<a href=\"https://covenanthealthproducts.com/need-product-help\"><strong>Questions About this Product?</strong></a>"}],"num_reviews":22,"weight":{"formatted":"0.00 Ounces","value":0},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$56.00","value":56},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=18299"},{"id":25534,"sku":"NEU-NE2054-NA","name":"Kavinace OS Emulsion 8oz","url":"https://covenanthealthproducts.com/kavinace-os-emulsion-8oz-by-neuroscience","availability":"This product is no longer available","rating":0,"brand":{"name":"NeuroScience"},"category":[],"summary":"Kavinace OS Emulsion 8oz by NeuroScienceKavinace OS Emulsion is a comprehensive blend of ingredients shown to improve the onset, duration, and efficiency of sleep. Contains proven ingredients to...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/25534/28330/kavinace-os-emulsion-8oz__30527.1638817139.jpg?c=1","alt":"Kavinace OS 60c by NeuroScience"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/25534/28330/kavinace-os-emulsion-8oz__30527.1638817139.jpg?c=1","alt":"Kavinace OS 60c by NeuroScience"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":false,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":140290,"name":"Brand","value":"<a href='/Neuroscience_c_2478.html'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/neuroscience_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":140291,"name":"Questions","value":"<a href=\"https://covenanthealthproducts.com/need-product-help\"><strong>Questions About this Product?</strong></a>"}],"num_reviews":0,"weight":{"formatted":"0.00 Ounces","value":0},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$27.00","value":27},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=25534"},{"id":27282,"sku":"NEU-NE1882","name":"Kavinace OS Blister Pack 14ct","url":"https://covenanthealthproducts.com/kavinace-os-14ct-neuroscience","availability":"Usually Ships in 48 to 72 Hours","rating":0,"brand":{"name":"NeuroScience"},"category":["Brands/Neuroscience Supplements and Vitamins"],"summary":"\nKavinace OS Blister Pack 14ct by NeuroScience\nKavinace OS by NeuroScience is a unique formulation designed to target the cellular effects of sleeplessness. It is scientifically formulated to provide...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/27282/29938/kavinace-os-14ct-neuroscience__08083.1651004287.jpg?c=1","alt":"Kavinace OS Blister Pack 14ct - NeuroScience"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/27282/29938/kavinace-os-14ct-neuroscience__08083.1651004287.jpg?c=1","alt":"Kavinace OS Blister Pack 14ct - NeuroScience"}],"date_added":"Apr 26, 2022","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":140336,"name":"Brand","value":"<a href='/Neuroscience_c_2478.html'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/neuroscience_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":140337,"name":"Questions","value":"<a href=\"https://covenanthealthproducts.com/need-product-help\"><strong>Questions About this Product?</strong></a>"}],"num_reviews":0,"weight":{"formatted":"0.00 Ounces","value":0},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$12.50","value":12.5},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=27282"},{"id":27202,"sku":"DF-TYM060","name":"Thyrommune 60c","url":"https://covenanthealthproducts.com/thyrommune-60c-designs-for-health/","availability":"Usually Ships in 48 to 72 Hours","rating":0,"brand":{"name":"Designs for Health"},"category":["Brands/Designs For Health Supplements and Vitamins"],"summary":"Thyrommune 60c by Designs for Health\nThyrommune™ by Designs for Health is a dietary supplement designed to support optimal thyroid function, healthy hormone balance, and a healthy immune system. This...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/27202/34269/Thyrommune-60c-designs-for-health__00662.1730142519.jpg?c=1","alt":"Thyrommune 60c by Designs for Health"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/27202/34269/Thyrommune-60c-designs-for-health__00662.1730142519.jpg?c=1","alt":"Thyrommune 60c by Designs for Health"}],"date_added":"Apr 18, 2022","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":131968,"name":"Brand","value":"<a href='/Designs-For-Health_c_35.html'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/designs-for-health_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":131969,"name":"Questions","value":"<a href=\"https://covenanthealthproducts.com/need-product-help\"><strong>Questions About this Product?</strong></a>"}],"num_reviews":0,"weight":{"formatted":"0.16 Ounces","value":0.16},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$25.99","value":25.99},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=27202"},{"id":27498,"sku":"EC2-GLYCLR60","name":"GlyphoDetox 60c","url":"https://covenanthealthproducts.com/glyphodetox-60c/","availability":"Usually Ships in 48 to 72 Hours","rating":0,"brand":{"name":"EcoNugenics"},"category":["Brands/Econugenics Supplements"],"summary":"\nGlyphoDetox by EcoNugenics - 60 Capsules\n\nGlyphoDetox provides advanced detox and defense against pesticides and other agricultural and environmental toxins. Powerful natural detox binders help...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/27498/32808/glypho-cleanse-60c-econugenics__64312.1713278446.jpg?c=1","alt":"GlyphoDetox by EcoNugenics - 60 Capsules"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/27498/32808/glypho-cleanse-60c-econugenics__64312.1713278446.jpg?c=1","alt":"GlyphoDetox by EcoNugenics - 60 Capsules"}],"date_added":"Aug 14, 2023","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":150832,"name":"Brand","value":"<a href='/Econugenics_c_2480.html'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/econugenics_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":150833,"name":"Questions","value":"<a href=\"https://covenanthealthproducts.com/need-product-help\"><strong>Questions About this Product?</strong></a>"},{"id":150834,"name":"Blog Post","value":"<a href=\"https://covenanthealthproducts.com/boost-your-longevity-with-modified-citrus-pectin-econugenics\"><strong>Information From Our Clinic</strong></a>"}],"num_reviews":0,"weight":{"formatted":"0.25 Ounces","value":0.25},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$52.00","value":52},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=27498"},{"id":21941,"sku":"CVR-CLAU16-NA","name":"Claudivastin 60c","url":"https://covenanthealthproducts.com/claudivastin-60c-by-ecological-formulas","availability":"This product is no longer available","rating":0,"brand":{"name":"Ecological Formulas"},"category":[],"summary":"Claudivastin 60c by Ecological FormulasClaudivastin by Ecological Formulas is scientifically designed to provide a direct release form of the physiologic agent, L-Carnitine. In human physiology,...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/21941/25943/EC0202PAR_0001__45030.1638817036.jpg?c=1","alt":"Claudivastin 60c by Ecological Formulas"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/21941/25943/EC0202PAR_0001__45030.1638817036.jpg?c=1","alt":"Claudivastin 60c by Ecological Formulas"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":false,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":133308,"name":"Brand","value":"<a href='/Ecological-Formulas_c_41.html'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/ecological-formulas_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":133309,"name":"Questions","value":"<a href=\"https://covenanthealthproducts.com/need-product-help\"><strong>Questions About this Product?</strong></a>"}],"num_reviews":0,"weight":{"formatted":"0.50 Ounces","value":0.5},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$27.95","value":27.95},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=21941"},{"id":23358,"sku":"DF-AGZ060","name":"AllerGzyme 60c","url":"https://covenanthealthproducts.com/allergzyme-60-capsules-by-designs-for-health","availability":"Usually Ships in 48 to 72 Hours","rating":0,"brand":{"name":"Designs for Health"},"category":["Brands/Designs For Health Supplements and Vitamins"],"summary":"AllerGzyme 60c by Designs for HealthDesigns for Health's AllerGzyme is a synergistic blend of enzymes designed to break down hard-to-digest proteins and reduce the adverse effects of occasional...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/23358/33701/AllerGzyme-60vc-designs-for-health__26535.1728760932.jpg?c=1","alt":"AllerGzyme 60c by Designs for Health"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/23358/33701/AllerGzyme-60vc-designs-for-health__26535.1728760932.jpg?c=1","alt":"AllerGzyme 60c by Designs for Health"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":131526,"name":"Brand","value":"<a href='/Designs-For-Health_c_35.html'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/designs-for-health_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":131527,"name":"Questions","value":"<a href=\"https://covenanthealthproducts.com/need-product-help\"><strong>Questions About this Product?</strong></a>"}],"num_reviews":0,"weight":{"formatted":"0.13 Ounces","value":0.13},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$46.99","value":46.99},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=23358"}],"shipping_messages":[],"rating":5,"reviews":{"messages":[],"captcha":"6LdWf8gSAAAAAI83aRectJhbwidegZKk8PzWBltH","total":21,"show_review_email":true,"end":21,"recaptcha":{"enabled":1,"public_key":"6LdWf8gSAAAAAI83aRectJhbwidegZKk8PzWBltH","markup":"<div class=\"g-recaptcha\" data-sitekey=\"6LcjX0sbAAAAACp92-MNpx66FT4pbIWh-FTDmkkz\"></div><br/>"},"start":19,"list":[{"name":"Sarah","rating":"4","title":"They Do Their Job Well","text":"I&#039;&#039;ve been taking 2 Kavinace capsules each night for about 14 months, to counteract the side effects of a prescription medication that I started taking around that time, which was making it difficult for me to fall asleep and would cause me to wake for no reason multiple times throughout the night. Since I started taking Kavinace, I have fallen asleep pretty quickly every night (probably within 10 minutes of closing my eyes). Although I still wake about three times each night, I quickly fall back asleep. The only remaining issue (and the only reason I rated Kavinace 4 stars instead of 5, though I&#039;&#039;m not 100% sure that Kavinace is the cause of the issue) is the extreme difficulty I have getting up in the morning, due to a strong desire to remain in bed and go back to sleep. However, once I manage to overcome that desire (usually after hitting &quot;snooze&quot; 2 times) and get going, I don&#039;&#039;t have any lingering drowsiness.","date":"Dec 14, 2014"},{"name":"Jose","rating":"5","title":"Mr","text":"This item works","date":"Dec 10, 2014"},{"name":"Kathryn Dunn","rating":"5","title":"Great Product!","text":"I love this product. It helps with anxiety and with sleep. I do not experience any side effects with it. If you are going to take more than one capsule, do so hours before bed so you are not groggy in the morning. This has happened for some people. I also take it during the day if I have anxiety symptoms and it works. I really have benefited from it.","date":"Dec 10, 2014"}]},"bulk_discount_rates":[],"title":"Kavinace 60c","gift_wrapping_available":false,"min_purchase_quantity":1}
Kavinace 60c by NeuroScience

Kavinace 60c

NeuroScience

$50.00
(21 reviews) Write a Review
SKU:
NS0014-NA
Availability:
This product is no longer available
Minimum Purchase:
1 unit
Brand:

Kavinace 60c by NeuroScience

Contains a blend of ingredients involved in the synthesis and activity of GABA, a neurotransmitter important for sleep*

GABA is the primary inhibitory neurotransmitter in the brain, meaning its central role is to balance excitability of neurons (1). Because of its function, GABA is important for promoting sleep, calm, and managing stress (2-4). Stress is thought to alter GABA synthesis and activity by affecting the expression of GABA-synthesizing enzymes and receptors (5).

Ingredients such as taurine and vitamin B6 are important for glutamate-GABA balance.* High glutamate can damage neurons, alter cellular homeostasis, and cause mitochondrial dysfunction, which can ultimately lead to cell death (6). Taurine demonstrates GABA-A agonist activity and protects neurons and mitochondria against glutamate-induced damage (6, 7).* Active form of vitamin B6 is important for the synthesis of GABA as it is a required cofactor for glutamate decarboxylase, the enzyme responsible for converting glutamate to GABA (8-10).*

References:

1. Gou Z, et al. Dongwuxue Yanjiu. 2012;33(E5-6):E75-81.
2. Mohler H. Neuropharmacology. 2012;62(1):42-53.
3. Saper C, et al. Nature. 2005;437(7063):1257-63.
4. Mody I and Maguire J. Front Cell Neurosci. 2012;6:4.
5. Maguire J. Front Cell Neurosci. 2014;8:157.
6. Ye H, et al. Can J Neurol Sci. 2013;40(5):628-34.
7. Kletke O, et al. PLoS One. 2013;8(4):e61733.
8. Rowley N, et al. Neurochem Int. 2012;61(4):546-58.
9. Martin D. Cell Mol Neurobiol. 1987;7(3):237-53.
10. Mukherjee T, et al. Biochim Biophys Acta. 2011;1814(11):1585-96.

Recommendation:
Take 1-2 capsules one to two times daily or as directed by your healthcare provider. Suggested at bedtime.

If you are pregnant or nursing, consult your healthcare provider before use.

Serving Size: 2 Capsules
Servings Per Container: 30

Amount Per Serving:
Vitamin B6 ... 2mg
(as pyridoxal 5-phosphate)
Proprietary Blend ... 950mg
Taurine and 4-amino-3-phenylbutyric acid HCl

Other Ingredients: Microcrystalline cellulose, Vegetable capsule (Hypromellose, water), and Magnesium stearate (vegetable source).

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  • 4
    They Do Their Job Well

    Posted by Sarah on Dec 14, 2014

    I''ve been taking 2 Kavinace capsules each night for about 14 months, to counteract the side effects of a prescription medication that I started taking around that time, which was making it difficult for me to fall asleep and would cause me to wake for no reason multiple times throughout the night. Since I started taking Kavinace, I have fallen asleep pretty quickly every night (probably within 10 minutes of closing my eyes). Although I still wake about three times each night, I quickly fall back asleep. The only remaining issue (and the only reason I rated Kavinace 4 stars instead of 5, though I''m not 100% sure that Kavinace is the cause of the issue) is the extreme difficulty I have getting up in the morning, due to a strong desire to remain in bed and go back to sleep. However, once I manage to overcome that desire (usually after hitting "snooze" 2 times) and get going, I don''t have any lingering drowsiness.

  • 5
    Mr

    Posted by Jose on Dec 10, 2014

    This item works

  • 5
    Great Product!

    Posted by Kathryn Dunn on Dec 10, 2014

    I love this product. It helps with anxiety and with sleep. I do not experience any side effects with it. If you are going to take more than one capsule, do so hours before bed so you are not groggy in the morning. This has happened for some people. I also take it during the day if I have anxiety symptoms and it works. I really have benefited from it.

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