Methyl B Complex

Methyl B Complex by Ortho Molecular Products – Methylated B Vitamins for Energy & Methylation Support

Methyl B Complex by Ortho Molecular Products is a professional-grade B complex supplement formulated with methylated B vitamins to support cellular energy, neurological health, and efficient methylation support. This advanced formula delivers highly bioavailable forms of Vitamin B12, Folate 5-MTHF, and complementary B nutrients for individuals who require optimal absorption and metabolic performance.

Key Methyl B Complex Benefits

• Supports sustained energy support and healthy metabolism
• Promotes efficient methylation support and homocysteine balance
• Aids cognitive function and nervous system health
• Supports cardiovascular and cellular wellness
• Provides bioavailable Vitamin B12 and Folate 5-MTHF for enhanced utilization

How Methyl B Complex Works

Methyl B Complex supplies a complete spectrum of B vitamins using forms aligned with current clinical and manufacturing standards for safety and absorption:

• Vitamin B12 (as methylcobalamin): Supports nerve function, red blood cell formation, and methylation pathways
• Folate (as Quatrefolic® 5-MTHF): Active folate that bypasses conversion steps, supporting DNA synthesis and cardiovascular health
• Vitamin B6 (as pyridoxine HCl): Assists amino acid metabolism and neurotransmitter production
• Thiamin, Riboflavin, Niacin, Pantothenic Acid: Essential cofactors for cellular energy and metabolic efficiency
• Choline & Inositol: Support liver health, cell membrane integrity, and fat metabolism

This methylated B vitamins formula is free from gluten, corn, yeast, and artificial colors or flavors. It is well tolerated when taken as directed, with minimal reported side effects.

Who Should Use Methyl B Complex

Methyl B Complex is ideal for adults seeking targeted support for energy levels, neurological health, cardiovascular wellness, or methylation support. It is especially beneficial for individuals with increased B-vitamin needs, genetic methylation challenges, or those looking for a clean, high-quality B complex supplement.

Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners. You may want to look at our other Multi-Vitamin products.

Recommendation: Ortho Molecular suggests taking 1 or more capsules of Methyl B Complex per day or as recommended by your health care professional.

Serving Size: 1 Capsule
Servings Per Container: 60 or 120

Amount Per Serving:
Thiamin (Vitamin B1) (from Thiamine Hydrochloride USP) 50 mg
Riboflavin (Vitamin B2 USP) 50 mg
Niacin (as Niacinamide USP) 50 mg
Vitamin B6 (as Pyridoxine
Hydrochloride USP) 50 mg
Folate (as Quatrefolic®
(6S)-5-Methyltetrahydrofolic
acid glucosamine salt) 400 mcg
Vitamin B12 (as Methylcobalamin) 500 mcg
Biotin 75 mcg
Pantothenic Acid (as d-Calcium
Pantothenate USP) 50 mg
Choline Bitartrate 19 mg
Inositol NF 50 mg

Other Ingredients: Natural Vegetable Capsules, Magnesium Stearate, Silicon Dioxide

Does Not Contain: gluten, corn, yeast, artificial colors, or flavors

Caution: If pregnant or nursing, consult your physician before use.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Click here to view Product Info Sheet

References:

1. 5-methyltetrahydofolate. Altern Med Rev. 2006;11(4).
2. Rindi G. "Thiamin." In: Ziegler E, Filer LJ, eds. Present Knowledge in Nutrition. International Life Sciences Institute; 1996:160-166.
3. Thiamine. Monograph. Altern Med Rev. Feb 2003;8(1):59-62.
4. Alaei Shahmiri F, Soares MJ, Zhao Y, Sherriff J. "High-dose thiamine supplementation improves glucose tolerance in hyperglycemic individuals: a randomized, double-blind crossover trial." Eur J Nutr. 2013 Oct;52(7):1821-4. Epub 2013 May 29.
5. Rivlin R. "Riboflavin." In: Ziegler E, Filer LJ, eds. Present Knowledge in Nutrition. International Life Sciences Institute; 1996:167-173.
6. Lee ES, Corfe BM, Powers HJ. "Riboflavin depletion of intestinal cells in vitro leads to impaired energy generation and enhanced oxidative stress." Eur J Nutr. 2013 Aug;52(5):1513-21. Epub 2012 Nov 6.
7. Wilson CP, Ward M, McNulty H, Strain JJ, Trouton TG, Horigan G, Purvis J, Scott JM. "Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-year follow-up." Am J Clin Nutr. 2012 Mar;95(3):766-72. Epub 2012 Jan 25.
8. Huskisson E, Maggini S, Ruf M. "The role of vitamins and minerals in energy metabolism and well-being." J Int Med Res. May-Jun 2007;35(3):277-289.
9. Sahebkar A. "Effect of niacin on endothelial function: A systematic review and meta-analysis of randomized controlled trials." Vasc Med. 2014 Jan 3. [Epub ahead of print].
10. Mason CM, Doneen AL. "Niacin-a critical component to the management of atherosclerosis: contemporary management of dyslipidemia to prevent, reduce, or reverse atherosclerotic cardiovascular disease." J Cardiovasc Nurs. 2012 Jul-Aug;27(4):303-16.
11. Leklem J. "Vitamin B-6." In: Ziegler E, Filer LJ, eds. Present Knowledge in Nutrition. International Life Sciences Institute; 1996:174-183.
12. Rimm EB, Willett WC, Hu FB, et al. "Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women." JAMA. 1998;279(5):359-364.
13. Meydani SN, Ribaya-Mercado JD, Russell RM, Sahyoun N, Morrow FD, Gershoff SN. "Vitamin B-6 deficiency impairs interleukin 2 production and lymphocyte proliferation in elderly adults." Am J Clin Nutr. 1991;53(5):1275-1280.
14. Talbott MC, Miller LT, Kerkvliet NI. "Pyridoxine supplementation: effect on lymphocyte responses in elderly persons." Am J Clin Nutr. 1987;46(4):659-664.
15. Rydlewicz A, Simpson JA, Taylor RJ, Bond CM, Golden MH. "The effect of folic acid supplementation on plasma homocysteine in an elderly population." QJM. Jan 2002;95(1):27-35.
16. Voutilainen S, Rissanen TH, Virtanen J, Lakka TA, Salonen JT. "Low dietary folate intake is associated with an excess incidence of acute coronary events: The Kuopio Ischemic Heart Disease Risk Factor Study." Circulation. 2001;103(22):2674-2680.
17. Penninx BW, Guralnik JM, Ferrucci L, Fried LP, Allen RH, Stabler SP. "Vitamin B(12) deficiency and depression in physically disabled older women: epidemiologic evidence from the Women’s Health and Aging Study." Am J Psychiatry. 2000 May;157(5):715-21.
18. Mock DM. "Biotin." In: Ziegler E, Filer LJ, eds. Present Knowledge in Nutrition. International Life Sciences Institute; 1996:220-235.
19. Sasaki Y, Sone H, Kamiyama S, Shimizu M, Shirakawa H, Kagawa Y, Komai M, Furukawa Y. "Administration of biotin prevents the development of insulin resistance in the skeletal muscles of Otsuka Long-Evans Tokushima Fatty rats." Food Funct. 2012 Apr;3(4):414-9. Epub 2012 Jan 5.
20. Hemmati M, Babaei H, Abdolsalehei M. "Survey of the effect of biotin on glycemic control and plasma lipid concentrations in type 1 diabetic patients in Kermanshah, Iran (2008-2009)." Oman Med J. 2013 May;28(3):195-8.
21. Plesofsky-Vig N. "Pantothenic Acid." In: Ziegler E, Filer LJ, eds. Present Knowledge in Nutrition. International Life Sciences Institute; 1996:236-244.
22. Naruta E, Buko V. "Hypolipidemic effect of pantothenic acid derivatives in mice with hypothalamic obesity induced by aurothioglucose." Exp Toxicol Pathol. 2001 Oct;53(5):393-8.
23. Ellinger S, Stehle P. "Efficacy of vitamin supplementation in situations with wound healing disorders: results from clinical intervention studies." Curr Opin Clin Nutr Metab Care. 2009 Nov;12(6):588-95. Review.
24. Zeisel SH, Blusztajn JK. "Choline and human nutrition." Annu Rev Nutr. 1994;14:269-96.
25. Hollenbeck CB. "An introduction to the nutrition and metabolism of choline." Cent Nerv Syst Agents Med Chem. Jun 2012;12(2):100-113.
26. da Costa KA, Niculescu MD, Craciunescu CN, Fischer LM, Zeisel SH. "Choline deficiency increases lymphocyte apoptosis and DNA damage in humans." Am J Clin Nutr. 2006 Jul;84(1):88-94.