CM Core - 90 CT by Ortho Molecular Products
CM Core – 90 CT is a cardiovascular health supplement formulated by Ortho Molecular Products.* It may provide multidimensional support for your whole cardiovascular system.* CM Core – 90 CT has a plethora of potential benefits for your health, including cholesterol level maintenance and supporting healthy blood sugar levels.* It may also help you reduce blood pressure, which makes it a versatile product for those seeking comprehensive cardiovascular health support.*
When Should You Consider CM Core - 90 CT by Ortho Molecular Products?
You may consider CM Core - 90 CT may support your health if you:
- eat a lot of fatty foods that may cause your cholesterol levels to skyrocket*
- have concerns about your heart health*
- you’re dealing with metabolic challenges and want to lose weight*
- you often feel fatigued*
CM Core - 90 CT—Potential Benefits
Ortho Molecular Products’ CM Core - 90 CT may benefit your health by:
- helping you maintain healthy blood pressure*
- promoting blood sugar balance*
- enhancing ATP production*
- maintaining healthy cholesterol levels if already within a normal range*
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Book a FREE product consultation to learn more about CM Core - 90 CT.
Recommendation:
Ortho Molecular Products suggests taking 3 CM Core capsules per day, or as directed by your healthcare professional.
Serving Size: 3 Capsules
Servings Per Container: 30
Amount Per Serving:
Vitamin C (As Ascorbyl Palmitate) 10 mg
Berberine Hydrochloride Hydrate 1 g
Alpha Lipoic Acid 200 mg
Other Ingredients: Natural Vegetable Capsules, Microcrystalline Cellulose, Magnesium Stearate, and Silicon Dioxide.
Does Not Contain: Gluten, corn, yeast, animal or dairy products, artificial colors, artificial flavors or preservatives.
Caution: If you are pregnant or nursing, consult your physician before taking this cardio vitamin.
References:
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- Jeong, H. W., Hsu, K. C., Lee, J. W., Ham, M., Huh, J. Y., Shin, H. J., Kim, W. S., & Kim, J. B. (2009). Berberine suppresses proinflammatory responses through AMPK activation in macrophages. American Journal of Physiology-Endocrinology and Metabolism, 296, E955–E964. https://doi.org/10.1152/ajpendo.90778.2008
- Kemp, B., Stapleton, D., Campbell, D., Chen, Z. P., Murthy, S., Walter, M., Gupta, A., Adams, J., Katsis, F., & van Denderen, B. (2003). AMP-activated protein kinase, super metabolic regulator. Biochemical Society Transactions, 31, 162–168. https://doi.org/10.1042/bst0310162
- Towler, M. C., & Hardie, D. G. (2007). AMP-activated protein kinase in metabolic control and insulin signaling. Circulation Research, 100, 328–341. https://doi.org/10.1161/01.RES.0000256090.42690.68
- Lau, C. W., Yao, X. Q., Chen, Z. Y., Ko, W. H., & Huang, Y. (2001). Cardiovascular actions of berberine. Cardiovascular Drug Reviews, 19, 234–244. https://doi.org/10.1111/j.1527-3466.2001.tb00136.x
- Brusq, J. M., Ancellin, N., Grondin, P., Guillard, R., Martin, S., Saintillan, Y., & Issandou, M. (2006). Inhibition of lipid synthesis through activation of AMP kinase: An additional mechanism for the hypolipidemic effects of berberine. Journal of Lipid Research, 47, 1281–1288. https://doi.org/10.1194/jlr.M500497-JLR200
- Kong, W., Wei, J., Abidi, P., Lin, M., Inaba, S., Li, C., Wang, Y., Wang, Z., Si, S., & Pan, H. (2004). Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nature Medicine, 10, 1344–1351. https://doi.org/10.1038/nm1135
- Derosa, G., D’Angelo, A., Bonaventura, A., Bianchi, L., Romano, D., & Maffioli, P. (2013). Effects of berberine on lipid profile in subjects with low cardiovascular risk. Expert Opinion on Biological Therapy, 13, 475–482. https://doi.org/10.1517/14712598.2013.758709
- Zhang, H., Wei, J., Xue, R., Wu, J. D., Zhao, W., Wang, Z. Z., Wang, S. K., Zhou, Z. X., Song, D. Q., & Wang, Y. M. (2010). Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression. Metabolism, 59, 285–292. https://doi.org/10.1016/j.metabol.2009.07.029
- Jäger, S., Handschin, C., Pierre, J. S., & Spiegelman, B. M. (2007). AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α. Proceedings of the National Academy of Sciences, 104, 12017–12022. https://doi.org/10.1073/pnas.0705070104
- Zhou, L., Yang, Y., Wang, X., Liu, S., Shang, W., Yuan, G., Li, F., Tang, J., Chen, M., & Chen, J. (2007). Berberine stimulates glucose transport through a mechanism distinct from insulin. Metabolism, 56, 405–412. https://doi.org/10.1016/j.metabol.2006.10.013
- Zhang, Q., Xiao, X., Feng, K., Wang, T., Li, W., Yuan, T., Sun, X., Sun, Q., Xiang, H., & Wang, H. (2011). Berberine moderates glucose and lipid metabolism through multipathway mechanism. Evidence-Based Complementary and Alternative Medicine, 2010, 1–10. https://doi.org/10.1155/2011/924589
- Shay, K. P., Moreau, R. F., Smith, E. J., Smith, A. R., & Hagen, T. M. (2009). Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential. Biochimica et Biophysica Acta (BBA)-General Subjects, 1790, 1149–1160. https://doi.org/10.1016/j.bbagen.2009.07.008
- Lee, W. J., Song, K. H., Koh, E. H., Won, J. C., Kim, H. S., Park, H. S., Kim, M. S., Kim, S. W., Lee, K. U., & Park, J. Y. (2005). α-Lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle. Biochemical and Biophysical Research Communications, 332, 885–891. https://doi.org/10.1016/j.bbrc.2005.05.064
- Ruderman, N. B., Carling, D., Prentki, M., & Cacicedo, J. M. (2013). AMPK, insulin resistance, and the metabolic syndrome. The Journal of Clinical Investigation, 123, 2764–2772. https://doi.org/10.1172/JCI67227
- Jacob, S., Ruus, P., Hermann, R., Tritschler, H., Maerker, E., Renn, W., Augustin, H., Dietze, G., & Rett, K. (1999). Oral administration of RAC-α-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: A placebo-controlled pilot trial. Free Radical Biology and Medicine, 27, 309–314. https://doi.org/10.1016/S0891-5849(99)00089-1
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Finally off of prescription blood pressure meds since taking this