Calm G 90c by Neuroscience
This product contains a blend of ingredients that are important for regulating glutamate activity, stress-reduction, metabolic health, and mitochondrial function.1 The key ingredients are N-acetyl-L-cysteine, L-theanine, Alpha-lipoic acid, and Coenzyme Q10. N-acetyl-L-cysteine is a precursor to L-cysteine, which is required for the synthesis of glutathione, an endogenous antioxidant important for mediating oxidative stress.2 L-theanine is an amino acid that acts as a glutamate receptor antagonist.3 Glutamatergic signaling underlies mechanisms related to anxiousness and stress.4 In a double-blind, placebo-controlled study, L-theanine was shown to significantly reduce stress.5 Alpha-lipoic acid is an antioxidant that is able to regenerate endogenous antioxidants and scavenge metal ions and free radicals.6 Evidence suggests the insulin-signaling pathway is sensitive to redox status. Alpha-lipoic acid can influence the redox status in cells important for the translocation of glucose transporters and increasing glucose uptake.7 Coenzyme Q10 is a compound found in nearly every human cell that is essential for mitochondrial function and antioxidant protection.8This product is unique in the marketplace because it combines these four ingredients into one blend, which may provide numerous benefits to the human body. It may help to reduce stress, regulate glutamate activity, improve metabolic health, and support mitochondrial function. Additionally, the combination of these ingredients may provide antioxidant protection and help to modulate the insulin-signaling pathway. While these statements have not been evaluated by the FDA, this product may be a beneficial supplement for those looking to support their wellbeing.References
1. Rushworth G and Megson I. Pharmacol Ther. 2014;141(2):150-9.
2. Schmitt B, et al. Redox Biol. 2015;6:198-205.
3. Kakuda T, et al. Biosci Biotechnol Biochem. 2002;66(12):2683-6.
4. Bermudo-Soriano C, et al. Pharmacol Biochem Behav. 2012;100(4):752-74.
5. Kimura K, et al. Biol Psychol. 2007;74(1):39-45.
6. Rochette L, et al. Can J Physiol Pharmacol. 2015;93(12):1021-7.
7. Garrido-Maraver J, et al. Front Biosci (Landmark Ed). 2014;19:619-33.
Recommendation:
Take 1-2 capsules three to four times daily or as directed by your healthcare provider.
If you are pregnant or nursing, consult your healthcare provider before use.
Serving Size: 2 Capsules
Serving per Container: 45
Amount Per Serving:
Folate ... 150mcg
(from (6S)-5-methyltetrahydrofolic acid, glucosamine salt**)
Selenium ... 70mcg
(as L-selenomethionine)
Proprietary Blend ... 1.1g
N-acetyl-L-cysteine, L-theanine, Alpha-lipoic acid, and Coenzyme Q10
Other Ingredients: Microcrystalline cellulose, Vegetable capsule (Hypromellose, water), and Magnesium stearate (vegetable source).
**This product uses Gnosis S.p.As (6S)-5-methyltetrahydrofolic acid, glucosamine salt (Quatrefolic®) and is protected by U.S. Patent No. 7, 947, 662. Quatrefolic is a registered trademark of Gnosis S.p.A., Milan, Italy.