{"num_reviews":0,"add_this":[{"service":"facebook","annotation":""},{"service":"twitter","annotation":""},{"service":"linkedin","annotation":""}],"gtin":null,"show_quantity_on_backorder":true,"brand":{"name":"Xymogen","url":"https://covenanthealthproducts.com/xymogen/"},"id":27549,"can_purchase":true,"meta_description":"Berberine ES-5 by Xymogen supports blood sugar balance and metabolic health with highly bioavailable dihydroberberine in a gentle, once-daily capsule.","category":["Brands/Xymogen Professional Formulas Supplements"],"AddThisServiceButtonMeta":"","main_image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/27549/38959/Berberine-ES-5-60c-Xymogen_45_11zon__20008.1767640346.jpg?c=1","alt":"Berberine ES-5 by Xymogen"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=27549","shipping":{"calculated":true},"custom_fields":[{"id":"150388","name":"Brand","value":"<a href='/brands/xymogen-professional-formulas/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/xymogen_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":"150389","name":"Questions","value":"<a href='/complimentary-product-consultation/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/need_someone_to_talk_to_250px.png\"></a><div><a href=\"/need-product-help\">Talk to an Expert</a></div>"}],"sku":"XY-300095624","backorder_availability_prompt":"More available for backorder","url":"https://covenanthealthproducts.com/berberine-es-5-60-c/","description":"<h2>Berberine ES-5 by Xymogen &ndash; Advanced Dihydroberberine for Blood Sugar Support</h2>\n<p><strong>Berberine ES-5 by Xymogen</strong> is a clinically advanced <strong>Xymogen Berberine</strong> formula designed to support healthy glucose metabolism and overall <strong>metabolic support</strong>. Featuring highly bioavailable <strong>dihydroberberine</strong>, this once-daily supplement offers efficient absorption with excellent tolerability for daily wellness routines.</p>\n<h3>Key Berberine ES-5 Benefits</h3>\n<ul>\n<li>Supports healthy <strong>blood sugar support</strong> already within the normal range</li>\n<li>Promotes <strong>insulin sensitivity</strong> and metabolic efficiency</li>\n<li>Provides enhanced absorption compared to standard berberine</li>\n<li><strong>Gentle</strong> on the digestive system for daily use</li>\n<li>Supports overall <strong>cardiometabolic health</strong></li>\n</ul>\n<h3>How Berberine ES-5 Works</h3>\n<p><strong>Berberine ES-5</strong> uses a next-generation form of berberine designed for improved bioavailability and minimal gastrointestinal discomfort.</p>\n<h4>Key Ingredient &amp; Mechanism:</h4>\n<ul>\n<li><a title=\"Berberine and health outcomes: An umbrella review\" href=\"https://pubmed.ncbi.nlm.nih.gov/36999891/\" target=\"_blank\" rel=\"noopener\"><strong>Dihydroberberine (200 mg)</strong></a>: A reduced form of berberine that converts efficiently in the body. Supports cellular glucose uptake and metabolic signaling. Designed to be well tolerated with <strong>minimal side effects</strong> when used as directed</li>\n</ul>\n<p>This formulation aligns fully with the manufacturer&rsquo;s ingredient profile, with no differences noted between listed and verified ingredients.</p>\n<h3>Who Should Use Berberine ES-5</h3>\n<p><strong>Berberine ES-5</strong> may be ideal for individuals who:</p>\n<ul>\n<li>Want targeted <strong>blood sugar support</strong> as part of a healthy lifestyle</li>\n<li>Are focused on improving <strong>insulin sensitivity</strong> and metabolic balance</li>\n<li>Prefer a once-daily, well-absorbed <strong>Xymogen Berberine</strong> supplement</li>\n<li>Seek metabolic support without harsh digestive effects</li>\n</ul>\n<p><strong>Supplements support your health but do not replace a balanced diet</strong>. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a <a title=\"Complimentary Product Consultation\" href=\"https://covenanthealthproducts.com/complimentary-product-consultation/\" target=\"_blank\" rel=\"noopener\"><strong>FREE product consultation</strong></a> with Holistic Health Partners. You may want to look at our other <a title=\"Blood Sugar Support Supplements\" href=\"https://covenanthealthproducts.com/clinic-recommended-products/blood-sugar-support/\" target=\"_blank\" rel=\"noopener\"><strong>Blood Sugar Support</strong></a> products.</p>\n<p><strong>Recommendation:</strong> Xymogen suggests taking 1 Berberine ES-5 capsule per day or as recommended by your healthcare professional.</p>\n<p><strong>Serving Size:</strong> 1 Capsule<br /><strong>Servings Per Container:</strong> 60</p>\n<div><strong>Amount Per Serving:</strong></div>\n<p>Dihydroberberine 200 mg</p>\n<p><strong>Other Ingredients:</strong> Microcrystalline cellulose, capsule (hypromellose and water), ascorbyl palmitate, and silica.</p>\n<p><strong>Storage:</strong> Keep closed in a cool, dry place out of reach of children.</p>\n<p><strong>Does Not Contain:</strong> Wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, sesame, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.</p>\n<p><em>These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.</em></p>\n<p><a title=\"Berberine ES-5 60 C - Xymogen\" href=\"../../../../content/Berberine-es-5-60c-data-sheet.pdf\" target=\"_blank\" rel=\"noopener\"><img src=\"../../../../product_images/uploaded_images/pdf20logo-sm.png\" alt=\"\" border=\"0px\" /> Click here to view Data Sheet</a></p>\n<hr />\n<p><small>LEGAL NOTICE: Xymogen's Exclusive Professional Formulas are available through select licensed health care professionals. The Internet Sale and Discounting of XYMOGEN formulas are strictly prohibited. covenanthealthproducts.com makes XYMOGEN formulas available only to patients of our clinic. If you are a patient of covenanthealthproducts.com, you may inquire about XYMOGEN by calling (800) 627-6518 </small><small></small></p>\n<p><strong>References:</strong></p>\n<ol>\n<li>Feng R, Shou JW, Zhao ZX, et al. Sci Rep. 2015;5:12155. doi:10.1038/srep12155</li>\n<li>Imenshahidi M, Hosseinzadeh H. Phytother Res. 2019;33(3):504-523. doi:10.1002/ptr.6252</li>\n<li>Moon J, Ratliff K, Hagele A, et al. Nutrients. 2021;14(1):124. doi:10.3390/nu14010124</li>\n<li>Zhang Q, Xiao X, Feng K, et al. Evid Based Complement Alternat Med. 2011;2011:924851. doi:10.1155/2011/924851</li>\n</ol>","show_backorder_message":true,"tags":[],"warranty":"","price":{"without_tax":{"formatted":"$53.99","value":53.99,"currency":"USD"},"tax_label":"Tax"},"detail_messages":"","availability":"Usually Ships in 48 to 72 Hours","page_title":"Berberine ES-5 60 C | Xymogen","cart_url":"https://covenanthealthproducts.com/cart.php","show_backorder_availability_prompt":true,"max_purchase_quantity":0,"show_quantity_on_hand":true,"mpn":"300095624","upc":"722537512244","options":[{"id":46213,"type":"Configurable_PickList_Set","display_name":"Recurring Order","required":true,"state":"modifier","partial":"set-select","condition":true,"values":[{"id":48845,"label":"One Time Purchase","selected":true,"data":"One Time Purchase"},{"id":48846,"label":"Every 20 Days","selected":false,"data":"Every 20 Days"},{"id":48847,"label":"Every 30 Days","selected":false,"data":"Every 30 Days"},{"id":48848,"label":"Every 40 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plant...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/26001/38960/Berberine-With-InSea2-60c-Xymogen_46_11zon__02328.1742290221.jpg?c=1","alt":"Berberine with InSea2 60 C - Xymogen"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/26001/38960/Berberine-With-InSea2-60c-Xymogen_46_11zon__02328.1742290221.jpg?c=1","alt":"Berberine with InSea2 60 C - Xymogen"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":150390,"name":"Brand","value":"<a href='/brands/xymogen-professional-formulas/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/xymogen_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":150391,"name":"Questions","value":"<a href='/complimentary-product-consultation/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/need_someone_to_talk_to_250px.png\"></a><div><a href=\"/need-product-help\">Talk to an Expert</a></div>"}],"num_reviews":0,"weight":{"formatted":"0.00 Ounces","value":0},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$83.99","value":83.99},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=26001"},{"id":25808,"sku":"BBRGT60","name":"Berberine GT 60 C","url":"https://covenanthealthproducts.com/berberine-gt-60-c-by-metagenics","availability":"Usually Ships in 48 to 72 Hours","rating":0,"brand":{"name":"Metagenics"},"category":["Brands/Metagenics","Clinic Recommended Products/Blood Sugar Support Supplements","Clinic Recommended Products/Blood Sugar Support Supplements/Berberine Supplements"],"summary":"Berberine GT 60 C by MetagenicsSupports cardiovascular health and healthy glucose metabolism*Berberine GT features berberine, an alkaloid compound found in the roots, rhizomes, stems and bark of...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/25808/37318/Berberine-GT-60c-Metagenics__21963.1739560335.jpg?c=1","alt":"Berberine GT 60 C by Metagenics"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/25808/37318/Berberine-GT-60c-Metagenics__21963.1739560335.jpg?c=1","alt":"Berberine GT 60 C by Metagenics"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":151436,"name":"Brand","value":"<a href='/brands/metagenics/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/metagenics_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":151437,"name":"Questions","value":"<a href='/complimentary-product-consultation/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/need_someone_to_talk_to_250px.png\"></a><div><a href=\"/need-product-help\">Talk to an Expert</a></div>"},{"id":151438,"name":"Clinic Approved","value":"Yes"},{"id":153807,"name":"How to Order","value":"<a href=\"/login.php\" style=\"width:183px;height:32px;background:#F27C03;color:#fff;font:12pt Arial;text-align:center;display:flex;justify-content:center;align-items:center;text-decoration:none;\">REGISTER TO ORDER</a>"},{"id":153808,"name":"Registered","value":"<a href=\"/login.php\" style=\"width:183px;height:32px;background:#F27C03;color:#fff;font:12pt Arial;text-align:center;display:flex;justify-content:center;align-items:center;text-decoration:none;\">LOGIN TO ORDER</a>"}],"num_reviews":0,"weight":{"formatted":"0.00 Ounces","value":0},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$44.00","value":44},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=25808"},{"id":18412,"sku":"XY-5MTHFES","name":"5-MTHF ES 60 C","url":"https://covenanthealthproducts.com/5-mthf-es-60-capsules-xymogen/","availability":"Usually Ships in 48 to 72 Hours","rating":0,"brand":{"name":"Xymogen"},"category":["Brands/Xymogen Professional Formulas Supplements","Brands/Xymogen","Clinic Recommended Products","Clinic Recommended Products/Methylation Support Supplements"],"summary":"5-MTHF ES 60 C by Xymogen\n5-MTHF ES is a premium supplement offering the most biologically active form of folate, 5-MTHF (5-methyltetrahydrofolate) in an amount of 17,000 mcg DFE, which the body can...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/18412/38916/5-MTHF-ES-60c-Xymogen_3_11zon__26109.1742212582.jpg?c=1","alt":"5-MTHF ES 60 C by 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Ounces","value":0},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$85.99","value":85.99},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=18412"},{"id":25990,"sku":"XY-300085998","name":"Berberine 120 C","url":"https://covenanthealthproducts.com/berberine-120-capsules-xymogen/","availability":"Usually Ships in 48 to 72 Hours","rating":5,"brand":{"name":"Xymogen"},"category":["Brands/Xymogen Professional Formulas Supplements"],"summary":"Berberine 120 C by Xymogen\nBerberine 120c is a blood sugar support supplement formulated by Xymogen, a brand known for its dedication to highly vetted, thoroughly researched formulas.* It contains...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/25990/38958/Berberine-120c-Xymogen_44_11zon__51058.1742290110.jpg?c=1","alt":"Berberine 120 C - Xymogen"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/25990/38958/Berberine-120c-Xymogen_44_11zon__51058.1742290110.jpg?c=1","alt":"Berberine 120 C - Xymogen"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":150386,"name":"Brand","value":"<a href='/brands/xymogen-professional-formulas/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/xymogen_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":150387,"name":"Questions","value":"<a href='/complimentary-product-consultation/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/need_someone_to_talk_to_250px.png\"></a><div><a href=\"/need-product-help\">Talk to an Expert</a></div>"}],"num_reviews":1,"weight":{"formatted":"0.00 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Berberine ES-5 60 C

Xymogen

$53.99
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SKU:
XY-300095624
UPC:
722537512244
Availability:
Usually Ships in 48 to 72 Hours
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1 unit
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Product Help Desk - Ask about products or ingredients or health conditions

Berberine ES-5 by Xymogen – Advanced Dihydroberberine for Blood Sugar Support

Berberine ES-5 by Xymogen is a clinically advanced Xymogen Berberine formula designed to support healthy glucose metabolism and overall metabolic support. Featuring highly bioavailable dihydroberberine, this once-daily supplement offers efficient absorption with excellent tolerability for daily wellness routines.

Key Berberine ES-5 Benefits

  • Supports healthy blood sugar support already within the normal range
  • Promotes insulin sensitivity and metabolic efficiency
  • Provides enhanced absorption compared to standard berberine
  • Gentle on the digestive system for daily use
  • Supports overall cardiometabolic health

How Berberine ES-5 Works

Berberine ES-5 uses a next-generation form of berberine designed for improved bioavailability and minimal gastrointestinal discomfort.

Key Ingredient & Mechanism:

  • Dihydroberberine (200 mg): A reduced form of berberine that converts efficiently in the body. Supports cellular glucose uptake and metabolic signaling. Designed to be well tolerated with minimal side effects when used as directed

This formulation aligns fully with the manufacturer’s ingredient profile, with no differences noted between listed and verified ingredients.

Who Should Use Berberine ES-5

Berberine ES-5 may be ideal for individuals who:

  • Want targeted blood sugar support as part of a healthy lifestyle
  • Are focused on improving insulin sensitivity and metabolic balance
  • Prefer a once-daily, well-absorbed Xymogen Berberine supplement
  • Seek metabolic support without harsh digestive effects

Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Or you may book a FREE product consultation with Holistic Health Partners. You may want to look at our other Blood Sugar Support products.

Recommendation: Xymogen suggests taking 1 Berberine ES-5 capsule per day or as recommended by your healthcare professional.

Serving Size: 1 Capsule
Servings Per Container: 60

Amount Per Serving:

Dihydroberberine 200 mg

Other Ingredients: Microcrystalline cellulose, capsule (hypromellose and water), ascorbyl palmitate, and silica.

Storage: Keep closed in a cool, dry place out of reach of children.

Does Not Contain: Wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, sesame, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

Click here to view Data Sheet


LEGAL NOTICE: Xymogen's Exclusive Professional Formulas are available through select licensed health care professionals. The Internet Sale and Discounting of XYMOGEN formulas are strictly prohibited. covenanthealthproducts.com makes XYMOGEN formulas available only to patients of our clinic. If you are a patient of covenanthealthproducts.com, you may inquire about XYMOGEN by calling (800) 627-6518

References:

  1. Feng R, Shou JW, Zhao ZX, et al. Sci Rep. 2015;5:12155. doi:10.1038/srep12155
  2. Imenshahidi M, Hosseinzadeh H. Phytother Res. 2019;33(3):504-523. doi:10.1002/ptr.6252
  3. Moon J, Ratliff K, Hagele A, et al. Nutrients. 2021;14(1):124. doi:10.3390/nu14010124
  4. Zhang Q, Xiao X, Feng K, et al. Evid Based Complement Alternat Med. 2011;2011:924851. doi:10.1155/2011/924851