AdreCor with Licorice Root 90c by NeuroScience
AdreCor with Licorice Root by NeuroScience contains a combination of non-glandular ingredients that are beneficial for adrenal health, energy, wakefulness, and stress management. The key ingredients include Glycyrrhizic Acid (from Licorice root extract), L-histidine, L-methionine, L-tyrosine, Rhodiola Rosea root extract (5% rosavins), Green tea leaf extract (Camellia sinensis) (65% EGCG), and vitamins B and C. Glycyrrhetinic acid (metabolite of glycyrrhizic acid) binds 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2) to inhibit the breakdown of cortisol (1,2). L-histidine is the precursor to histamine, which plays an important role in the release of pituitary hormones and wakefulness (3). L-methionine is the precursor to S-adenosylmethionine (SAMe), which is directly involved in methylation processes, including catecholamine synthesis (4). L-tyrosine is the precursor to catecholamines, including dopamine, norepinephrine, and epinephrine. Rhodiola Rosea is an adaptogen that has been shown to reduce stress-induced effects (5,6). In a randomized, double-blind, placebo-controlled study, Rhodiola Rosea was shown to significantly improve mental fatigue and general well-being under stress (7). Green tea leaf extract (Camellia sinensis) contains epigallocatechin gallate (EGCG), a polyphenol that provides antioxidant protection by its ability to scavenge free radicals and metal ions (8). EGCG has been shown to increase resistance to fatigue in animal models (9). Finally, active forms of pantothenic acid, niacin, B6, folate, B12, and C are important for the synthesis of adrenal hormones and neurotransmitters (10-14). This combination of ingredients is unique in the marketplace as it provides a comprehensive approach to supporting adrenal health, energy, wakefulness, and stress management. It can help to address symptoms of fatigue, stress, and low energy, while providing antioxidant protection.References
1. van Gelderen C, et al. Hum Exp Toxicol. 2000;19(8):434-9.
2. Chapman K, et al. Physiol Rev. 2013;93(3):1139-206.
3. Krystal A, et al. Sleep Med Rev. 2013;17(4):263-72.
4. Duncan T, et al. Mol Nutr Food Res. 2013;57(4):628-36.
5. Mischoulon D and Fava M. Am J Clin Nutr. 2002;76(5):1158S-61S.
6. Chiang H, et al. J Food Drug Anal. 2015;23(3):359-69.
7. Spasov A, et al. Phytomedicine. 2000;7(2):85-9.
8. Legeay S, et al. Nutrients. 2015;7(7):5443-68.
9. Teng Y and Wu D. Pharmacogn Mag. 2017;13(50):326-31.
10. Ragaller V, et al. J Anim Physiol Anim Nutr (Berl). 2011;95(1):6-16.
11. Vrecko K, et al. Biochim Biophys Acta. 1997;1361(1):59-65.
12. May J, et al. Brain Res Bull. 2013;90:35-42.
13. Antoniades C, et al. Circulation. 2006;114(11):1193-201.
14 Mattson M and Shea T. Trends Neurosci. 2003;26(3):137-46.
Recommendation:
Take 1-3 capsules one to two times daily or as directed by your healthcare provider.
If you have cardiovascular concerns or if you are pregnant or nursing, consult your healthcare provider before use.
Serving Size: 3 Capsules
Servings Per Container: 30
Amount Per Serving:
Vitamin C ... 300mg
(as ascorbic acid)
Niacin ... 6mg
(as niacinamide)
Vitamin B6 ... 12mg
(as pyridoxal 5-phosphate)
Folate ... 120mcg
(from (6S)-5-methyltetrahydrofolic acid, glucosamine salt**)
Vitamin B12 ... 60mcg
(as methylcobalamin)
Panthothenic acid ... 300mg
(as D-calcium pantothenate)
Magnesium ... 14mg
(as magnesium bisglycinate chelate)
Zinc ... 3mg
(as zinc bisglycinate chelate)
Glycyrrhizic acid ... 120mg
(from Licorice root extract)
Proprietary Blend ... 587mg
L-histidine, L-methionine, L-tyrosine, Rhodiola Rosea root extract (5% rosavins), and Green tea (Camellia sinensis) leaf extract (65% epigallocatechin gallate)
Other Ingredients: Microcrystalline cellulose, Vegetable capsule (Hypromellose, water), and Magnesium stearate (vegetable source).
**This product uses Gnosis S.p.As (6S)-5-methyltetrahydrofolic acid, glucosamine salt (Quatrefolic®) and is protected by U.S. Patent No. 7, 947, 662. Quatrefolic is a registered trademark of Gnosis S.p.A., Milan, Italy.