{"num_reviews":0,"url":"https://covenanthealthproducts.com/5-mthf-es-60-capsules-xymogen/","add_this":[{"service":"facebook","annotation":""},{"service":"twitter","annotation":""},{"service":"linkedin","annotation":""}],"gtin":null,"brand":{"name":"Xymogen","url":"https://covenanthealthproducts.com/xymogen/"},"id":18412,"can_purchase":true,"meta_description":"Enjoy the benefits of 5-MTHF with our ES supplement! Get free shipping when you purchase now. Support your body's natural processes!","category":["Brands/Xymogen Professional Formulas Supplements","Brands/Xymogen","Clinic Recommended Products","Clinic Recommended Products/Methylation Support Supplements"],"AddThisServiceButtonMeta":"","main_image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/18412/32763/5-mthf-es-60-capsules-xymogen__16536.1712860184.jpg?c=1","alt":"5-MTHF ES 60 C by Xymogen"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=18412","shipping":{"calculated":true},"custom_fields":[{"id":"150332","name":"Brand","value":"<a href='/brands/xymogen-professional-formulas/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/xymogen_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":"150333","name":"Questions","value":"<a href='/complimentary-product-consultation/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/need_someone_to_talk_to_250px.png\"></a><div><a href=\"/need-product-help\">Talk to an Expert</a></div>"}],"sku":"XY-5MTHFES","description":"<h3>5-MTHF ES 60 C by Xymogen</h3>\n<p><strong>5-MTHF ES</strong> is a premium supplement offering the most biologically active form of folate, 5-MTHF (5-methyltetrahydrofolate) in an amount of 17,000 mcg DFE, which the body can use directly.* Unlike folic acid, which requires conversion in the body, 5-MTHF is deployed ready to support essential processes like <a href=\"https://covenanthealthproducts.com/clinic-recommended-products/methylation-support-supplements/\">methylation</a> and brain function.* As it may contribute to the development of the nervous system in the fetus, this supplement is great for pregnant women.* Quatrefolic&mdash;the glucosamine salt of 5-MTHF used in 5-MTHF ES 60 C by Xymogen has been tested both in vitro and in vivo to assure its safety.* 5-MTHF ES provides effective folate replenishment so that the body can use it to synthesize DNA, neurotransmitters and produce melanin.* This product promotes healthy homocysteine metabolism, and supports normal cellular proliferation, including red blood cells, without the risks of unmetabolized folic acid accumulation.*</p>\n<h3>Who Should Consider 5-MTHF ES 60 C by Xymogen?</h3>\n<p><strong>5-MTHF ES by Xymogen may support your health if you:</strong></p>\n<ul>\n<li>are pregnant or planning to become pregnant*</li>\n<li>want to support your overall nervous system health*</li>\n<li>want to improve your cardiovascular health*</li>\n</ul>\n<h3>5-MTHF ES 60 C by Xymogen&mdash;Effects?</h3>\n<p><strong>5-MTHF ES may:</strong></p>\n<ul>\n<li>support healthy serum folate levels and help prevent folate deficiency*</li>\n<li>enhance crucial brain and metabolic processes*</li>\n<li>help maintain and support healthy cardiovascular function*</li>\n</ul>\n<p><strong>Supplements support your health but do not replace a balanced diet. </strong>Always check with your healthcare practitioner if you have doubts about a new supplement. Book a <a href=\"https://covenanthealthproducts.com/complimentary-product-consultation/\">FREE product consultation</a> to learn more about 5-MTHF ES 60 C by Xymogen.</p>\n<p><strong>Recommendation:</strong><strong><br /></strong><strong>Xymogen</strong> suggests taking <strong>1 or 2 capsules of 5-MTHF ES</strong> per day or as recommended by your healthcare professional.</p>\n<p><strong>Serving Size:</strong> 2 Capsules<br /><strong>Servings Per Container:</strong> 30<br /><br /><strong>Amount Per Serving:</strong><br />Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt)<sup>S1</sup> 17,000 mcg DFE<br /><br /><strong>Other Ingredients:</strong>&nbsp;Microcrystalline cellulose, HPMC (capsule), stearic acid, magnesium stearate, and silica.<br /><br /><strong>Does Not Contain: </strong>Wheat, gluten, corn, yeast, soy, animal or dairy products,&nbsp;fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically&nbsp;modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial&nbsp;preservatives.<br /><br /><strong>Caution: </strong>Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional. Do not use if tamper seal is damaged.<br /><br /><strong>Storage: </strong>Keep tightly closed in a cool, dry place out of reach of children.</p>\n<p><strong>Trademarks:<br /></strong>S1. Quatrefolic<sup>&reg;</sup>&nbsp;is a registered trademark of Gnosis S.p.A. Produced under U.S. Patent 7,947,662.</p>\n<p><br /><br /><img src=\"../../../../product_images/uploaded_images/pdf20logo-sm.png\" alt=\"\" border=\"0px\" /> <a title=\"5-MTHF ES 60 C - Xymogen\" href=\"../../../../content/xymogen-5-mthf-products-drs.pdf\" target=\"_blank\" rel=\"noopener\">Click here to view Data Sheet</a></p>\n<hr />\n<p><small>LEGAL NOTICE: Xymogen's Exclusive Professional Formulas are available through select licensed health care professionals. The Internet Sale and Discounting of XYMOGEN formulas are strictly prohibited. covenanthealthproducts.com makes XYMOGEN formulas available only to patients of our clinic. If you are a patient of covenanthealthproducts.com, you may inquire about XYMOGEN by calling (800) 627-6518</small></p>\n<p><strong>References:</strong></p>\n<ol>\n<li><em><em>Prinz-Langenohl R, Br&auml;mswig S, Tobolski O, et al. (2009 Dec) [6S]-5-methyltetrahydrofolate increases plasma folate more effectively than folic acid in women with the homozygous or wild-type 677C--&gt;T polymorphism of methylenetetrahydrofolate reductase. Br J Pharmacol;158(8):2014- 21.</em></em></li>\n<li><em>Yakut M, Ust&uuml;n Y, Kaba&ccedil;am G, et al. (2010 Aug) Serum vitamin B12 and folate status in patients with inflammatory bowel diseases. Eur J Intern Med;21(4):320-23.</em></li>\n<li><em>Venn BJ, Green TJ, Moser R, et al. ( 2003 Mar) Comparison of the effect of low-dose supplementation with L-5-methyltetrahydrofolate or folic acid on plasma homocysteine: a randomized placebo-controlled study. Am J Clin Nutr;77(3):658-62.&nbsp;</em></li>\n<li><em>5-methyltetrahydrofolate. Monograph. Altern Med Rev. 2006 Dec;11(4):330-37.</em></li>\n<li><em>Willems FF, Boers GH, Blom HJ, et al. (. 2004 Mar) Pharmacokinetic study on the utilisation of 5-methyltetrahydrofolate and folic acid in patients with coronary artery disease. Br J Pharmacol141(5):825-30.</em></li>\n<li><em>&nbsp;Scaglione F, Panzavolta G. ( 2014 May) Folate, folic acid and 5-methyltetrahydrofolate are not the same thing. Xenobiotica;44(5):480-8.</em></li>\n<li><em>Crossover Comparative Bioavailability Study of 5-Methyltetrahydrofolate Glucosamine Salt (GN10G) Compared to the Reference Metafolin&reg; in Healthy Volunteers. IPAS-5MTHFA-583-09 final report. Desio, Italy: Gnosis S.p.A.; March 15, 2010: 1-33.</em></li>\n</ol>","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$83.99","value":83.99,"currency":"USD"},"tax_label":"Tax"},"detail_messages":"","availability":"Usually Ships in 48 to 72 Hours","page_title":"5-MTHF ES 60 C by Xymogen - Covenant Health Products","cart_url":"https://covenanthealthproducts.com/cart.php","max_purchase_quantity":0,"mpn":"300000089","upc":"871149003623","options":[{"id":37234,"type":"Configurable_PickList_Set","display_name":"Recurring Order","required":true,"condition":false,"state":"modifier","values":[{"label":"One Time Purchase","id":48845,"data":"One Time Purchase","selected":true},{"label":"Every 20 Days","id":48846,"data":"Every 20 Days","selected":false},{"label":"Every 30 Days","id":48847,"data":"Every 30 Days","selected":false},{"label":"Every 40 Days","id":48848,"data":"Every 40 Days","selected":false},{"label":"Every 45 Days","id":159647,"data":"Every 45 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as...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/16069/35255/5-MTHF-1mg-60c-Thorne__40085.1733687765.jpg?c=1","alt":"5-MTHF 1mg 60c by Thorne"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/16069/35255/5-MTHF-1mg-60c-Thorne__40085.1733687765.jpg?c=1","alt":"5-MTHF 1mg 60c by Thorne"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":148880,"name":"Brand","value":"<a href='/brands/thorne/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/thorne_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":148881,"name":"Questions","value":"<a href='/complimentary-product-consultation/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/need_someone_to_talk_to_250px.png\"></a><div><a href=\"/need-product-help\">Talk to an Expert</a></div>"}],"num_reviews":0,"weight":{"formatted":"0.00 Ounces","value":0},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$24.00","value":24},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=16069"},{"id":16921,"sku":"DF-MTH120","name":"L-5-MTHF 1700mcg 120c","url":"https://covenanthealthproducts.com/l-5-mthf-120-capsules-by-designs-for-health","availability":"Usually Ships in 48 to 72 Hours","rating":5,"brand":{"name":"Designs for Health"},"category":["Brands/Designs For Health Supplements and Vitamins"],"summary":"\nL-5-MTHF 120c by Designs for Health \nL-5-MTHF by Designs for Health is a natural form of folate, which is an essential nutrient for cell growth and division, as well as helping to balance the...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/16921/37759/L-5-MTHF-1700mcg-DFE-120c-designs-for-health__18605.1740052149.jpg?c=1","alt":"L-5-MTHF 120c by Designs for Health"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/16921/37759/L-5-MTHF-1700mcg-DFE-120c-designs-for-health__18605.1740052149.jpg?c=1","alt":"L-5-MTHF 120c by Designs for Health"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":131728,"name":"Brand","value":"<a href='/brands/designs-for-health/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/designs-for-health_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":131729,"name":"Questions","value":"<a href='/complimentary-product-consultation/'><img 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This...","image":{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/17609/32762/5-mthf-60-capsules-xymogen__59294.1712859966.jpg?c=1","alt":"5-MTHF 60 C by Xymogen"},"images":[{"data":"https://cdn11.bigcommerce.com/s-35tuw7jhw2/images/stencil/{:size}/products/17609/32762/5-mthf-60-capsules-xymogen__59294.1712859966.jpg?c=1","alt":"5-MTHF 60 C by Xymogen"}],"date_added":"Dec 06, 2021","pre_order":false,"show_cart_action":true,"has_options":true,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":150330,"name":"Brand","value":"<a href='/brands/xymogen-professional-formulas/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/brand-logos/xymogen_278x90.png\" width=\"278\" height=\"90\"></a>"},{"id":150331,"name":"Questions","value":"<a href='/complimentary-product-consultation/'><img src=https://cdn11.bigcommerce.com/s-35tuw7jhw2/product_images/uploaded_images/need_someone_to_talk_to_250px.png\"></a><div><a href=\"/need-product-help\">Talk to an Expert</a></div>"}],"num_reviews":1,"weight":{"formatted":"0.00 Ounces","value":0},"demo":false,"price":{"without_tax":{"currency":"USD","formatted":"$32.99","value":32.99},"tax_label":"Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=17609"},{"id":17658,"sku":"TH-B132","name":"5-MTHF 5mg 60c","url":"https://covenanthealthproducts.com/5-mthf-5mg-60-capsules-by-thorne","availability":"Usually Ships in 48 to 72 Hours","rating":5,"brand":{"name":"Thorne"},"category":["Brands/Thorne Supplements and Vitamins"],"summary":"5-MTHF 5mg 60c by Thorne&nbsp;5-MTHF by Thorne is a biologically active form of the B-vitamin folic acid. 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5-MTHF ES 60 C by Xymogen

5-MTHF ES 60 C

Xymogen

$83.99
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SKU:
XY-5MTHFES
UPC:
871149003623
Availability:
Usually Ships in 48 to 72 Hours
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1 unit
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Product Help Desk - Ask about products or ingredients or health conditions

5-MTHF ES 60 C by Xymogen

5-MTHF ES is a premium supplement offering the most biologically active form of folate, 5-MTHF (5-methyltetrahydrofolate) in an amount of 17,000 mcg DFE, which the body can use directly.* Unlike folic acid, which requires conversion in the body, 5-MTHF is deployed ready to support essential processes like methylation and brain function.* As it may contribute to the development of the nervous system in the fetus, this supplement is great for pregnant women.* Quatrefolic—the glucosamine salt of 5-MTHF used in 5-MTHF ES 60 C by Xymogen has been tested both in vitro and in vivo to assure its safety.* 5-MTHF ES provides effective folate replenishment so that the body can use it to synthesize DNA, neurotransmitters and produce melanin.* This product promotes healthy homocysteine metabolism, and supports normal cellular proliferation, including red blood cells, without the risks of unmetabolized folic acid accumulation.*

Who Should Consider 5-MTHF ES 60 C by Xymogen?

5-MTHF ES by Xymogen may support your health if you:

  • are pregnant or planning to become pregnant*
  • want to support your overall nervous system health*
  • want to improve your cardiovascular health*

5-MTHF ES 60 C by Xymogen—Effects?

5-MTHF ES may:

  • support healthy serum folate levels and help prevent folate deficiency*
  • enhance crucial brain and metabolic processes*
  • help maintain and support healthy cardiovascular function*

Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Book a FREE product consultation to learn more about 5-MTHF ES 60 C by Xymogen.

Recommendation:
Xymogen suggests taking 1 or 2 capsules of 5-MTHF ES per day or as recommended by your healthcare professional.

Serving Size: 2 Capsules
Servings Per Container: 30

Amount Per Serving:
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt)S1 17,000 mcg DFE

Other Ingredients: Microcrystalline cellulose, HPMC (capsule), stearic acid, magnesium stearate, and silica.

Does Not Contain: Wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

Caution: Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional. Do not use if tamper seal is damaged.

Storage: Keep tightly closed in a cool, dry place out of reach of children.

Trademarks:
S1. Quatrefolic® is a registered trademark of Gnosis S.p.A. Produced under U.S. Patent 7,947,662.



Click here to view Data Sheet

LEGAL NOTICE: Xymogen's Exclusive Professional Formulas are available through select licensed health care professionals. The Internet Sale and Discounting of XYMOGEN formulas are strictly prohibited. covenanthealthproducts.com makes XYMOGEN formulas available only to patients of our clinic. If you are a patient of covenanthealthproducts.com, you may inquire about XYMOGEN by calling (800) 627-6518

References:

  1. Prinz-Langenohl R, Brämswig S, Tobolski O, et al. (2009 Dec) [6S]-5-methyltetrahydrofolate increases plasma folate more effectively than folic acid in women with the homozygous or wild-type 677C-->T polymorphism of methylenetetrahydrofolate reductase. Br J Pharmacol;158(8):2014- 21.
  2. Yakut M, Ustün Y, Kabaçam G, et al. (2010 Aug) Serum vitamin B12 and folate status in patients with inflammatory bowel diseases. Eur J Intern Med;21(4):320-23.
  3. Venn BJ, Green TJ, Moser R, et al. ( 2003 Mar) Comparison of the effect of low-dose supplementation with L-5-methyltetrahydrofolate or folic acid on plasma homocysteine: a randomized placebo-controlled study. Am J Clin Nutr;77(3):658-62. 
  4. 5-methyltetrahydrofolate. Monograph. Altern Med Rev. 2006 Dec;11(4):330-37.
  5. Willems FF, Boers GH, Blom HJ, et al. (. 2004 Mar) Pharmacokinetic study on the utilisation of 5-methyltetrahydrofolate and folic acid in patients with coronary artery disease. Br J Pharmacol141(5):825-30.
  6.  Scaglione F, Panzavolta G. ( 2014 May) Folate, folic acid and 5-methyltetrahydrofolate are not the same thing. Xenobiotica;44(5):480-8.
  7. Crossover Comparative Bioavailability Study of 5-Methyltetrahydrofolate Glucosamine Salt (GN10G) Compared to the Reference Metafolin® in Healthy Volunteers. IPAS-5MTHFA-583-09 final report. Desio, Italy: Gnosis S.p.A.; March 15, 2010: 1-33.
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