Histamine is a chemical substance that is naturally produced by the body's immune system in response to injury or infection. In the digestive system, histamine plays a role in regulating the secretion of stomach acid and in controlling the movement of food through the intestines.

However, in some people, histamine can cause an allergic reaction, leading to symptoms such as hives, itching, sneezing, nasal congestion, and digestive problems. This is known as histamine intolerance or histamine sensitivity.

Certain foods can trigger histamine reactions in people who are sensitive to it. These foods include:

1. Fermented foods: Fermented foods such as sauerkraut, kimchi, kefir, and yogurt are high in histamine.

2. Aged or cured meats: Meats such as salami, ham, and bacon are high in histamine.

3. Cheese: Aged cheeses such as cheddar, blue cheese, and parmesan are high in histamine.

4. Seafood: Shellfish and certain types of fish, such as mackerel, tuna, and sardines, are high in histamine.

5. Tomatoes and spinach: These vegetables are naturally high in histamine.

6. Citrus fruits: Oranges, lemons, and grapefruits are high in histamine.

7. Nuts: Certain types of nuts, such as cashews and walnuts, are high in histamine.

It's important to note that not everyone who consumes these foods will have a histamine reaction. People who are sensitive to histamine may also have other food intolerances or allergies, which can make it difficult to identify the root cause of their symptoms. If you suspect that you have a histamine intolerance, it's important to talk to a healthcare professional to determine the best course of action.

Diamine oxidase (DAO) is an enzyme that plays a crucial role in breaking down histamine in the body. DAO is primarily found in the digestive tract, where it breaks down histamine that is present in food or produced by the body. People with histamine intolerance may have a deficiency in DAO, so they are unable to break down histamine effectively. Supplementation with DAO may help to alleviate these symptoms by increasing the body's ability to metabolize excess histamine. DAO supplements are available and can be taken before meals to support this process. However, it is important to note that DAO supplements are not a cure-all solution, and other lifestyle changes, such as avoiding high-histamine foods and reducing stress, may also be necessary to manage symptoms effectively.

HistDAO by Xymogen is an excellent option for anyone who is experiencing symptoms of histamine intolerance. This includes people who have been diagnosed with histamine intolerance by a healthcare provider or who suspect that they may have the condition based on their symptoms.

HistDAO is also a good choice for anyone who is looking to support their digestive health. DAO plays a crucial role in the breakdown of histamine in the gut, so taking HistDAO can help to promote optimal gut function.

In addition, HistDAO may be beneficial for people who are looking to support their immune function. Histamine is a crucial component of the immune response, and excessive histamine levels can lead to chronic inflammation and other immune-related issues.

Overall, this is a great supplement for anyone looking to support their digestive health and improve histamine metabolism. Reach out to someone at our clinic today to discuss whether HistDAO, or another alternative may be right for you.