4Sight - by Ortho Molecular Products
4Sight is an excellent eye health supplement designed by Ortho Molecular Products, a brand well known for its science-first approach and transparency.* You may take it not only to support your eye health in general but also when aging, to promote macular health, which often deteriorates when you get older.*
Who May Consider 4Sight by Ortho Molecular Products?
Consider taking 4Sight if you:
- do not consume sufficient amounts of eye-health-support nutrients in your diet*
- are aging*
How May 4Sight Benefit Your Health?
Potentially, 4Sight by Ortho Molecular Products can:
- increase ocular circulation*
- support eye antioxidation*
- promote macular health when aging*
Supplements support your health but do not replace a balanced diet. Always check with your healthcare practitioner if you have doubts about a new supplement. Book a FREE product consultation to learn more about 4Sight.
Recommendation:
Ortho Molecular Products suggests taking 2 capsules per day or as recommended by your health care professional.
Serving Size: 2 Capsules
Servings Per Container: 30 or 60
Amount Per Serving:
Zinc (as TRAACS® Zinc Bisglycinate Chelate) 15 mg
Taurine 400 mg
N-Acetyl-L-Cysteine USP 200 mg
Bilberry Fruit Extract 150 mg (Standardized to contain 25% Anthocyanidins)
Alpha Lipoic Acid 150 mg
Quercetin Dihydrate 100 mg
Ginkgo biloba Leaf Extract 60 mg (Standardized to contain 24% Ginkgo
Flavone Glycosides and 6% Terpene Lactones)
Lutein 30 mg
Lycopene 6 mg
Zeaxanthin 1.5 mg
Other Ingredients: Natural Vegetable Capsules, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, and Stearic Acid.
Click here to view the Product Info Sheet
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
References:
- Maitra, I., Serbinova, E., Tritschler, H. J., & Packer, L. (1996). Stereospecific effects of R-lipoic acid on buthione sulfoximine-induced cataract formation in newborn rats. Biochemical and Biophysical Research Communications, 221(2), 422-429.
- Li, Y., Liu, Y. Z., Shi, J. M., & Jia, S. B. (2013). Alpha lipoic acid protects lens from H₂O₂-induced cataract by inhibiting apoptosis of lens epithelial cells and inducing activation of anti-oxidative enzymes. Asian Pacific Journal of Tropical Medicine, 6(7), 548-551.
- Lee, W. J., Song, K. H., Koh, E. H., et al. (2005). Alpha-lipoic acid increases insulin sensitivity by activating AMPK in skeletal muscle. Biochemical and Biophysical Research Communications, 332(3), 885-891.
- Osler, M. E., & Zierath, J. R. (2008). Minireview: Adenosine 5’-monophosphate-activated protein kinase regulation of fatty acid oxidation in skeletal muscle. Endocrinology, 149, 935-941.
- Ruderman, N. B., Saha, A. K., & Kraegen, E. W. (2003). Minireview: Malonyl CoA, AMP-activated protein kinase, and adiposity. Endocrinology, 144, 5166-5171.
- Ahlemeyer, B., & Krieglstein, J. (2003). Neuroprotective effects of Ginkgo biloba extract. Cellular and Molecular Life Sciences, 60(9), 1779-1792.
- Ahlemeyer, B., & Krieglstein, J. (2003). Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer’s disease. Pharmacopsychiatry, 36(Suppl 1), S8-S14.
- Ponto, L. L., & Schultz, S. K. (2003). Ginkgo biloba extract: Review of CNS effects. Annals of Clinical Psychiatry, 15(2), 109-119.
- Droy-Lefaix, M. T., Vennat, J. C., Besse, G., & Doly, M. (1992). Effects of Ginkgo biloba extract (EGb 761) on chloroquine induced retinal alterations. Lens and Eye Toxic Research, 9(3-4), 521-528.
- Droy-Lefaix, M. T., Cluzel, J., Menerath, J. M., et al. (1995). Antioxidant effect of a Ginkgo biloba extract (Egb 761) on the retina. International Journal of Tissue Reactions, 17(3), 93-100.
- Szabo, M. E., Droy-Lefaix, M. T., & Doly, M. (1997). Direct measurement of free radicals in ischemic/reperfused diabetic rat retina. Clinical Neuroscience, 4(5), 240-245.
- Abdel-Aal el-SM., Akhtar, H., Zaheer, K., & Ali, R. (2013). Dietary sources of lutein and zeaxanthin carotenoids and their role in eye health. Nutrients, 5(4), 1169-1185.
- Koushan, K., Rusovici, R., Li, W., Ferguson, L.R., & Chalam K.V. (2013). The role of lutein in eye-related disease. Nutrients, 5(5), 1823-1839.
- Gao, S., Qin, T., Liu, Z., Caceres, M.A., Ronchi C.F., Chen C.Y., Yeum K.J., Taylor A., Blumberg J.B., Liu Y., & Shang F. (2011). Lutein and zeaxanthin supplementation reduces H₂O₂-induced oxidative damage in human lens epithelial cells. Molecular Vision, 17, 3180-3190.
- Seddon, J.M., Ajani U.A., Sperduto R.D., et al. (1994). Dietary carotenoids, vitamin A,C and E and advanced age-related macular degeneration: Eye Disease Case-Control Study Group.JAMA, 272(18), 1413-1420.
- Arnold C., Winter L., Fröhlich K., Jentsch S., Dawczynski J., Jahreis G., & Böhm V.(2013). Macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration: A randomized trial.JAMA Ophthalmology, 131(5), 564-572.
- Nicolas M.G., Fujiki K., Murayama K.et al.(1996). Studies on the mechanism of early onset macular degeneration in cynomolgus monkeys II: Suppression of metallothionein synthesis in the retina in oxidative stress.Experimental Eye Research, 62(4),399-408.
- Cingle K.A., Kalski R.S., Bruner W.E.et al.(1996). Age-related changes of glycosidases in human retinal pigment epithelium.Current Eye Research, 15(4),433-438.
- Wyszynski R.E., Bruner W.E.Cano D.B.et al.(1989). A donor-age-dependent change in the activity of alpha-mannosidase in human cultured RPE cells.Investigative Ophthalmology & Visual Science, 30(11),2341-2347.
- Yao N., Lan F., He R.R.& Kurihara H.J.(2010). Protective effects of bilberry (Vaccinium myrtillus L.) extract against endotoxin-induced uveitis in mice.Agricultural and Food Chemistry, 58(8),4731-4736.
- Canter P.H.& Ernst E.(2004). Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision: A systematic review of placebo-controlled trials.Survey of Ophthalmology, 49(1),38-50.
- Song J.Li Y.Ge J.et al.(2010). Protective effect of bilberry (Vaccinium myrtillus L.) extracts on cultured human corneal limbal epithelial cells (HCLEC).Phytotherapy Research, 24(4),520-524.
- Bito T.Roy S.Sen C.K.et al.(2002). Flavonoids differentially regulate IFN gamma-induced ICAM-1 expression in human keratinocytes: Molecular mechanisms of action.FEBS Letters,520(1-3),145-152.
- Amasheh M.Schlichter S.Amasheh S.et al.(2008). Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells.Journal of Nutrition,138(6),1067-1073.
- Penissi A.B.Rudolph M.I.Piezzi R.S.(2003). Role of mast cells in gastrointestinal mucosal defense.Biocell,27(2),163-172.
- Lombardini J.B.(1991). Taurine: Retinal function.Brain Research Reviews,16(2),151-169.